嘧啶碱基 pyrimidine base,嘧啶核的各部分被取代的化合物。和嘌呤碱基一样,在生物体内以核酸、核苷酸、核苷等的成分而存在,游离态的比较少见。
这些甲基团只粘附于特定胞嘧啶碱基- DNA四个组成成分之一。
The methyl groups are attached only to specific cytosine bases - one of the four building blocks of DNA.
在DNA甲基化的胞嘧啶碱基在许多真核生物的表观遗传调控提供了一层正常的生物学和疾病有着重要的意义。
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease.
问题的答案隐藏在人类的第15号染色体中的相关区域,其中含有等位胸腺嘧啶碱基(T)编号为rs1051730SNP才是“罪魁祸首”。
That answer lies in part of human chromosome 15, and depends on what is known as allele T of SNP rs1051730.
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