皮肤鳞状细胞癌与基底细胞癌9号染色体杂合性丢失及PTCH1表达的研究 - docin.com豆丁网 发生相关的不同的遗传学基础。 皮肤肿瘤的发生也是多因素、多阶段、多基因共同作用所致,涉及多种癌基 因的激活和抑癌基因(tumorsuppressorgene,TSG)的失活。等位基因的缺失表 现为多态位点的杂合性丢失(10ssof heterozygosity,LO
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有巨大的癌基因和抑癌基因的癌症有关。
There are enormous oncogenes and suppressor genes involved in cancer.
目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
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