... Haworth methylation 霍沃思甲基化法 Promoter methylation 启动子甲基化 maintenance methylation 维持甲基化 ...
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目的建立甲基化特异性PCR（MSP）技术检测黏着斑激酶相关性鸟苷三磷酸酶调节因子（GRAF）基因启动子甲基化。
Objective To establish the methylation-specific PCR(MSP) to detect methylation of GTPase regulator associated with the focal adhesion kinase(GRAF) gene promoter.
结论肝细胞癌中CHFR基因、EDNRB基因启动子的高甲基化是普遍现象，而3 - OST - 2基因启动子甲基化率较低。
Conclusion promoter methylation of CHFR and EDNRB genes is a common event in HCC, while frequency of promoter methylation of 3-ost-2 is rather low.
正常对照骨髓HPP-CFC P16基因启动子甲基化阳性率较高，而银屑病患者骨髓HPP-CFC P16基因启动子甲基化阳性率低于正常人。
The positive frequency of methylation of P16 gene promoter in HPP-CFC of normal contrasts was higher than that of psoriatic patients.
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