文章详细信息 关键词： 层黏连蛋白;;胰腺癌;;化疗耐药;;黏着斑激酶 [gap=1875]Keywords: laminin;pancreatic cancer;chemoresistance;focal adhesion kinase
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Level of p53 protein expression can predict well chemoresistance and chemoresponsiveness of cervical cancer.
p53蛋白的表达情况能很好地预测宫颈癌的化疗耐药与反应。
参考来源 - p53蛋白在化疗前后Ⅰ、Ⅱ期巨块宫颈癌组织中的表达 Expression of p53 Protein in Stage Ⅰ、ⅡFurthermore, Pol B is an error-prone enzyme and its fidelity of repair is low, so the outstretched function would induce inheritance instability and drug resistance.
而且pol β是一个错误倾向的聚合酶，其复制保真度低，故pol β扩张的功能可能导致遗传不稳定及化疗耐药的发生。
参考来源 - 食管癌中DNA聚合酶β蛋白高表达与对顺铂产生耐药性之间的关系Objective:Chemotherapy resistance of malignant tumor is the tough problem to solve now.
研究背景、目的化疗耐药是目前恶性肿瘤治疗中急需解决的难题。
参考来源 - 丙戊酸增强人卵巢癌耐药细胞株COC1/DDP对顺铂敏感性的研究Conclusions The positive rate of expression of MDR-1 in ovarian cancer tissues are high,which is related to drug-resistance. The mechanism may be that MDR-1 can inhibit the expression of Wnt-1,FZD-1 gene.
结论卵巢癌组织中MDR-1基因有较高的阳性表达率,与卵巢癌的化疗耐药有关,MDR-1基因可能通过抑制Wnt-1、FZD-1基因的表达而发挥作用。
参考来源 - 卵巢癌组织中MDR·2,447,543篇论文数据，部分数据来源于NoteExpress
热疗可导致化疗耐药的产生。
结论这些基因表达差异与卵巢癌化疗耐药有关。
Conclusion These genes related to the mechnisms of drug-resistance of ovarian cancer.
目的研究血清细胞角蛋白18 (CK18)水平与非小细胞肺癌患者紫杉醇化疗耐药的关系。
Objective to investigate the relationship between serum cytokeratin 18 (CK18) levels and resistance to paclitaxel chemotherapy in patients with non-small cell lung cancer.
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