本文研究了反相高效液相色谱和超速冷冻离心测定雷公藤甲素聚乳酸纳米粒包封率和载药量的方法。
The encapsulation efficiency and drug loading of triptolide-loaded poly (d, L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study.
结论:本实验制备的HCPT - SSLN包封率和载药量较高,粒径分布均匀,稳定性良好。初步表明HCPT适合进行SSLN包裹。
Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.
结果表明,所得微球粒径适合,分布均匀,性质稳定,载药量和包封率均比较适宜。
The results showed that the particle size and distribution was suitable, quality was stable, drug-loaded and entrapment rate were fine.
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