患者还可能对某种药物产生耐受性，这意味着患者必须服用比以往更大的剂量才能产生预期的效果。

A patient may also acquire a tolerance for a certain drug, which means the patient has to take ever larger doses to produce the desired effect.

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就像瘾君子一样，市场需要越来越大的剂量，才能达到同样的效果。

Markets, like addicts, need bigger and bigger doses to get the same effect.

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给予大剂量维生素会产生一定的效果是刚刚才被认识到。

Vitamins given in high doses may also have effects that science is only beginning to understand.

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Now, the polio vaccine that Salk produced was very effective, but it required a fairly large dose of the vaccine and it had to be injected into the arms of children.

索尔克生产的小儿麻痹症疫苗效果显著,但是,该疫苗的单支注射剂量非常大,而且必须通过小孩的手臂进行注射

耶鲁公开课 - 生物医学工程探索课程节选