我们发现鼠类MSC分泌高水平的IL - 6和血管内皮生长因子,两者可直接抑制T细胞增殖。
We show that murine MSC secrete high levels of interleukin (IL) -6 and vascular endothelial growth factor, which are directly correlated to the inhibition of T-cell proliferation.
本研究探讨骨髓内皮细胞分泌的造血抑制因子在扩增造血祖细胞中的作用并初步探讨其作用机制。
In this study, the roles of hematopoietic inhibitors elaborated by bone marrow endothelial cells in the proliferation and differentiation of hematopoietic progenitors were investigated.
结论:RSV对T细胞的免疫抑制作用,可能与其抑制T细胞的活化、增殖和细胞因子的分泌有关。
CONCLUSION: The immunosuppressive action of RSV may be related with its inhibitory effects on t cell activation, proliferation and cytokine expression.
应用推荐