药物的溶解性，在胃肠道中的稳定性，膜的通透性和全身代谢是影响口服药物吸收的主要因素。
The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
因此，研究全身相关因素的影响作用十分重要。
Therefore, it is very important to study the influences and functions of related systemic factors.
而高温高湿环境下颅脑火器伤既有湿热环境对全身各系统功能影响，又有颅脑火器伤对颅脑功能的机械性损害，二者因素相互作用造成机体更加严重地损伤。
The two factors, the hot and humid environment having a negative effect on all systems and CMW leading to the brain mechanical injuries, work together so as to cause a more serious wound.
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