血液中咖啡因水平的增加会阻碍腺苷的作用，导致血管收缩，最终则可能导致心脏病发作。埃尔-索海米说，在这项研究中，大约有55%的人携带有减缓咖啡因代谢的基因。
Increased levels of circulating caffeine may block adenosine's action, causing blood vessels to constrict, subsequently triggering a heart attack, says El-Sohemy.
甲状腺素用于控制你的新陈代谢，如果太多或太少就会阻碍你脑细胞之间正常的沟通。
Thyroid hormones control your metabolism, but too much or too little can disrupt the normal chatter between brain cells.
这些在分子与细胞水平的变化渐渐积累，最终会阻碍代谢，病理问题因而产生。
Gradually those changes at the molecular and cellular level accumulate and accumulate and eventually they start to get in the way of metabolism, and that's where pathology comes.
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