他绝望了，希望都破灭了。

He is in despair. All hope is gone.

youdao

这次失败使他绝望了。

The failure drove him into despair.

youdao

他绝望地放弃了斗争。

He gave up the struggle in despair.

《牛津词典》

Do you see that word "throbs"? " A desperate honesty that throbs through his confession."

你们看到那个字了吗，悸动“,他的忏悔被绝望的虔诚悸动着“

耶鲁公开课 - 1945年后的美国小说课程节选

They were wandering in the forests and he was in despair, having lost everything.

他们在森林里流浪,那勒陷入绝望,他失去了一切

耶鲁公开课 - 金融市场课程节选

Dante He mentions Virgil and Dante, and it seems like the desperation of bringing up such grand figures makes me think that he does have doubts.

他提到了Virgil和，提到的那些伟大的人物时他的绝望,让我觉得他也心存疑惑。

耶鲁公开课 - 1945年后的美国小说课程节选