目的研制针对人补体膜攻击复合物（MAC）新抗原的特异性单克隆抗体。

Objective To prepare monoclonal antibody (McAb) against neoantigen of the human complement membrane attack complex (MAC).

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衰变加速因子（DAF） 是补体激活途径中的一个重要膜调节蛋白， 转人DAF 基因猪可以作为人器官移植的供体。

Decay accelerating factor(DAF)is one of the important membrane regulating protein in the complement activating ways. The transgenic pigs for human DAF gene can used for xenotransplatations donors.

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构建突变人CD59分子（HMCD59）真核表达体系，探讨HMCD59糖基化前后抗补体活性的变化。

To construct human mutant CD59(HMCD59) eukaryot ic expression system and investigate whether glycation could inhibit the protection role of HMCD59 against human complement.

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