珍爱的东西无可挽回地失去了，做什么也都于事无补了。
Something treasured had been irretrievably lost, and there was nothing to be done about it.
心中再有不舍，不忍心和过去的甜蜜说再见，也于事无补了。
Reluctant to say goodbye to the past sweet as we are, our efforts are unavailing.
你现在已经打碎花瓶了！说什么都于事无补了。我们得买个新的了。
You've broken the vase now! There's no use crying over spilt milk. We will buy a new one.
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