方法用紫外分光光度法测定该制剂中盐酸二甲双胍的含量, 高效液相色谱法测定格列吡嗪的含量。
Methods The content of dimethydiguanide was determined by ultraviolet spectrophotometry, and the content of glipizide was determined by high-performance liquid chromatography(HPLC).
结论:本方法准确、快速、简便,可不经分离直接测定复方盐酸二甲双胍片中盐酸二甲双胍的含量。
CONCLUSION: the method is accurate, fast, convenient, and which can be used to determine the contents of metformin hydrochloride in compound metformin hydrochloride tablets directly without isolation.
盐酸二甲双胍是目前广泛用于临床医学的双胍类降糖药。
Metformin hydrochloride is an orally administered biguanide widely used in clinical medicine.
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