对重组乙型肝炎（乙肝） 病毒前S1 抗原（1- 42 ）及核心抗原（1- 144 ）表达的融合蛋白CS1进行了免疫原性的研究分析，以便为探索HBV治疗性疫苗的研制提供实验依据。

The aim of this study was to express a fusion protein of HBV preS1 Ag(1-42) and HBcAg(1-144) and analyze its immunogenicity for further study of HBV therapeutic vaccine.

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目的探讨采用乙型肝炎免疫球蛋白（HBIG）阻断孕妇乙型肝炎病毒（HBV）感染对新生儿乙型肝炎（简称乙肝）基因疫苗免疫效果的影响。

AbstractObjectiveTo explore the effect on neonatal immunization with hepatitis B gene vaccine by interrupting HBV infection in pregnant women with HBIG 200IU.

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