目的:探讨高脂饲料诱导的肥胖(diet-inducedobesity,DIO)与肥胖抵抗(diet-inducedobesityresistance,DIO-R)大鼠不同易感性的差异及血清中蛋白表达。
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肥胖与胰岛素抵抗有关,是2型糖尿病、心脏病、高血压和其他慢性病的危险因素。
Associated with insulin resistance, obesity is a risk factor for type 2 diabetes, heart disease, hypertension and other chronic illnesses.
其中胰岛素抵抗、高胰岛素血症与肥胖关系密切。
The relationship between obesity and insulin resistance, hyperinsulinemia is consanguineous.
肥胖者空腹血清瘦素水平与胰岛素抵抗密切相关,是胰岛素抵抗的主要相关因素,而这一关系仅在男性中存在。
Fasting serum leptin level closely correlated with insulin resistance in obese subjects and it was the main correlation factor of insulin resistance, but the relationship only existed in male.
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