任何一个小小的中断，一个价格检查，一个喋喋不休的顾客，都会产生下游效应，拖住整个队伍。

Any small interruption—a price check, a chatty customer—can have downstream effects, holding up an entire line.

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目前，一共有11种蛋白被鉴定是这个通路的组成成分，并确定了一些下游效应靶点蛋白。

So far, 11 proteins have been identified as members of this pathway, and several downstream effector proteins have been determined.

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指出上游水资源开发对地处霍林河下游半干旱区域的科尔沁国家级自然保护区湿地带来的负面效应；

This paper presents negative effect of the water resources development to Keerqin wetlands of state nature reserve located semiarid area in downstream of the Huolin River.

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