《大西洋月刊》长期以来一直试图提供一种设计环境，让文学和新闻两种不同的传统保有尊严、愉悦共存。

The Atlantic Monthly has long attempted to provide a design environment in which two disparate traditions—literary and journalistic—can co-exist in pleasurable dignity.

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没有任何一种设计能够适用于所有地方。建设比设计更重要。

No design is well received everywhere. Construction is more important than design.

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一种设计效果很好，反复应用于其他地方，加上一些看似没什么影响的改进，突然有一天它就不奏效了。

Perhaps a design works so well. It is adopted elsewhere again and again, with seemingly harmless improvements, until, suddenly, it does not work at all anymore.

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Part two was that they had to design a new product service that Merrill Lynch never offered before.

其次是他们要设计一种,美林未推出的新产品。

麻省理工公开课 - 媒体、教育、市场课程节选

So, the antigen we're thinking about is a vaccine particularly designed to elicit immune response against a pathogen.

我们现在考虑的这种抗原,是一种特别设计的疫苗,它能够诱发免疫效应以消灭病原体

耶鲁公开课 - 生物医学工程探索课程节选

Should it be customized, or in other words, made specific for the particular audience or can we create something that is an off-the-shelf product that people can use in many different environments?

应该为特定的受众，量身设计教育过程,还是制造,一种现成的产品,以供人们,在多种不同环境中使用？

麻省理工公开课 - 媒体、教育、市场课程节选