结论：颅底手术中采用适宜的外科技术和修复材料进行一期颅底修补，对于减少术后感染、脑脊液鼻漏等并发症有重要意义。

Conclusion:Immediate reconstruction of skull base with suitable material and surgical technique can prevente complications such as postoperative infection and cerebrospinal leakage brain hernation.

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一期肠修补或切除吻合术39例（75 % ） ，二期肠造口或肠外置术13例（2 5 % ）。发生肠瘘2例，死亡5例。

There were 39(75%) patients were treated with primary repair or resection and anastomosis, and 13(25%) with diverting colostomy, 2 cases colon leakage, 5 cases died.

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目的通过对2 1例急性开放性颅骨粉碎性凹陷骨折一期整复、修补治疗结果分析，提出急性开放性颅骨粉碎凹陷性骨折一期整复、修补的手术适应症。

Objectives To propose suit methods of the first restoring and mending acute comminuted open and depressed fractures with the analysis of the operation result in 21 cases.

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