目的研究细胞间信息传递机制之一假单胞菌喹诺酮信号（PQS）在铜绿假单胞菌发病机制中的作用。
Objective To study the unique cell-to-cell communication mechanism of Pseudomonas quinolone signal(PQS) in the pathogenesis of Pseudomonas aeruginosa.
提出了一种合成芳基氟喹诺酮抗菌剂二氟沙星和替马沙星的新方法。
A new synthetic method for preparing two arylfluoroquinolone antimicrobial agents, difloxacin and temafloxacin, was reported.
结论菌株对氟喹诺酮和第三代头孢菌素敏感，是目前临床治疗伤寒的一线药物，也是多重耐药菌株所致伤寒的首选药物。
Some strains were cross-resistant. Conclusions They are first-line drugs to treat typhoid fever, especially typhoid fever caused by multiple drug-resistant strain.
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