thrombin

英/ ˈθrɒmbɪn /

美/ ˈθrɑːmbɪn /

1
[生化] 凝血酶
...幼鼠脑水肿变化(脑水含量)、神经元凋亡以及小胶质细胞MAPK/ERK信号通路磷酸化情况;离体培养原代小胶质细胞,使用凝血酶(Thrombin,红细胞裂解产物之一)作为至伤物构建离体脑出血单一因素环境,观察小胶质细胞在凝血酶以及JWH133干预后的增殖情况以及MAPK/ERK信号...
2
凝血
作用机转: 肝素先与抗凝血第三因子(Antithrombin III)结合,进而加速凝血 (thrombin)之去活性作用,而达成抗凝血作用。肝素也可与多种凝血因子(IIa、Xa、XIa、XIIa)结合,使之失去活性。
3
凝血酶冻干粉
品名称】通用名称：凝血酶冻干粉英文名称：Thrombin汉语拼音：Ningxuemei Dongganfen【成份】本品为牛血或猪血中提取的凝血酶原，经激活而得凝血酶的无菌冻干品。每1mg 效价不得少于10单位。含凝

短语

1
Thrombomodulin can entirely inhibit thrombin and ristocetin-induced platelet aggregation.
血栓调节蛋白可完全抑制凝血酶和利斯托司汀诱导的血小板聚集。
2
Express ancrod, a snake venom thrombin-like enzyme, in methylotrophic yeast Pichia pastoris.
利用毕赤酵母表达具有生物学活性的蛇毒类凝血酶安克洛。
3
Using this technique, they were able to detect sub-femtomolar (10-12) concentrations of thrombin in human serum.
利用这种技术，他们能够在人体血清中检测出浓度低至femtomolar（10-12 摩尔/升）的凝血酶。

Thrombin
Thrombin (EC 3.4.21.5, fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.

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