frameshift

英/ ˈfreɪmˌʃɪft /

美/ ˈfreɪmˌʃɪft /

1
[遗] 移码
移码的(frameshift), 此释义来源于网络辞典。
2
移码突变
医学遗传学基础词语中英文对照 ... forward 正向突变 frame-shift 移码突变 gene 基因突变 ...
3
[遗] 框移
... 列表 tabulation; summarizing; ent ... 框移 frameshift 掉 fall; drop; shed; come off ...

短语

1
Both frameshift and missense mutations can be suppressed by intragenic suppressors.
移码突变和异义突变都能被基因内抑制基因所抑制。
2
Both frameshift and missense mutations can be suppressed by intragenic suppressors.
两个突变发生在同一基因内的抑制，叫基因内抑制。
3
Results all samples of water have plenty of direct mutagen and a small amount of indirect mutagen of base frameshift mutation.
结果各水样中有大量的碱基移码型的直接致突变物和少量的需经代谢活化的碱基移码型的直接致突变物。

Frameshift
Translational frameshifting or ribosomal frameshifting refers to an alternate process of protein translation. A protein is translated from one end of the mRNA to the other, from the 5' to the 3' end. Normally a protein is translated from a template mRNA with consecutive blocks of 3 nucleotides being read as single amino acids. However, certain organisms may exhibit a change or shift in the ribosomes frame by one or two nucleotides when translating the genetic code. This is deemed translational or ribosomal frameshifting. The process can be programmed by the nucleotide sequence of the mRNA and is sometimes affected by the secondary or tertiary mRNA structure. It has been described mainly in viruses (especially retroviruses), retrotransposons and bacterial insertion elements, and also in some cellular genes.

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