Vinyl sulfonate monomers were experimentally found of lower reactivity and couldn't effectively copolymerize with MMA and MAA.

Its branch chains having double bond can copolymerize with vinyl monomers (such as styrene or vinyl toluene) forming a thermosetting resin.

Poly(p-dioxanone) has high degree of crystallinity which limited it to copolymerize with other monomers to be used as controlled drug release materials.