1.  puzzle
2.  problem
3.  challenge
4.  conundrum
5.  knot

• 1. 难题: problem | puzzle | A Gordian Knot | question
• 2. 恶的难题: problem of evil | The problem of evil
• 3. 破解发展难题: to solve problems hindering development

更多释义

• 1.她处理起这种难题来方法很巧妙。
  She handles this difficult subject with a light touch.
  dict.yoduao.com
• 2.他们试图用一道难题难倒她。
  They tried to catch her out with a difficult question.
  dict.yoduao.com
• 3.这将是我们的一大难题。
  This is going to be a huge problem for us.
  dict.yoduao.com

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