1.  fling caution to the winds
2.  regardlessness
3.  go to the most extreme lengths to

• 1. 不顾一切: Us Against The World | Reckless | Drop everything now | at any risk
• 2. 不顾一切的: desperate | devil-may-care | temerarious | reckless
• 3. 不顾一切地: regardless ad | Desperately | recklessly | full tear

更多释义

• 1.人们不顾一切地抢占最好的座位。
  There was a mad scramble for the best seats.
  dict.yoduao.com
• 2.他钟情于她，达到了不顾一切的地步。
  His passion for her made him blind to everything else.
  dict.yoduao.com
• 3.他不顾一切地试图说明情况是多么紧急。
  He tried desperately to convey how urgent the situation was.
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