目的：探讨肾移植患者中影响麦考酚酸（MPA）游离分数的因素。
OBJECTIVE To investigate the factors affecting the unbound fraction of mycophenolic acid(MPA) in renal transplant recipients.
麦考酚吗乙酯是麦考酚酸的2-乙基酯前体药物，临床广泛应用于器官移植后的抗排斥治疗。
Mycophenolate mofetil, the prodrug of the 2-(4morpholino) ethyl ester of mycophenolic acid, has been widely applied to the prophylaxis of acute graft rejection in solid organ transplantation.
麦考酚酸表现出一种特殊的抗丙肝病毒复制的作用机制，它不依赖细胞增殖及鸟嘌呤核苷消耗。
MPA was shown to hae a distinct anti-HC mechanism of action, independent of cell proliferation and guanosine depletion.
麦考酚酸是一种普通的青霉菌代谢物，于二十世纪三十年代首次报道，是一种可能的真菌毒素。
Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin.
对麦考酚酸的重新研究显示其具有广泛的药理学活性，如抗肿瘤、抗病毒、抗真菌和抗原生动物等。
Re-investigation has shown mycophenolic acid to display a broad range of pharmacological activities including antitumor, antiviral, antifungal and antiprotozoan activities.
对麦考酚酸的重新研究显示其具有广泛的药理学活性，如抗肿瘤、抗病毒、抗真菌和抗原生动物等。
Re-investigation has shown mycophenolic acid to display a broad range of pharmacological activities including antitumor, antiviral, antifungal and antiprotozoan activities.
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