最初引文摘要：自体软骨细胞移植治疗距骨骨软骨缺损（2006；88：303-8）。
ORIGINAL ABSTRACT CITATION: "Autologous Chondrocyte Transplantation for Treating Cartilage Defects of the Talus" (2006; 88:303-8).
临床上运用干细胞治疗骨软骨缺损，股骨头坏死，脊髓神经损伤等骨科疾病方面已取得了很多成果。
Stem cells for treating osteochondral defect, femoral head necrosis and spinal nerve injury have obtained many achievements in clinic.
目的：观察膝关节骨软骨缺损及表面软骨缺损动物模型关节软骨组织中胶原及基质金属蛋白酶的表达变化。
OBJECTIVE: To explore the expressions of MMP and collagen in cartilage tissues in knee articular cartilages defects and surface defects models.
结果：全椎板切除后在椎板缺损部位纤维化，首先是在骨组织缺损的边缘软骨组织形成，然后再演变为骨组织，最后形成再生椎板。
Results: There was fibrous tissue in the defect of lamina after laminectomy. First formed cartilaginous tissue in fibrous, and then evolved into osseous tissues, and finally into.
非软骨类组织和材料只能阻止小面积生长板缺损内骨桥形成，无再生修复能力。
Non cartilaginous tissue and material could only prevent formation of bony bridge in small defect of growth plate and lacked ability of regenerative repair.
制造兔甲状软骨缺损模型，于缺损处分别植入肌肉、单纯异种骨及重组合骨。
The models of thyroid cartilage defect were established a nd then muscle, bone xenograft and RBX were implanted into the three groups respectively.
对关节透明软骨缺损有软骨面清理术、软骨下骨穿孔术、软骨移植术和药物治疗，但确定采用那一种方法，需要对软骨状况有个真实的了解。
The recent development of surgical and pathophysiologic methods for the treatment of articular cartilage abnormalities has created a need for the accurate, noninvasive evaluation of chondral lesions.
非软骨组织材料只能阻止小面积生长板缺损内骨桥形成，无再生修复能力。
Noncartilaginous tissue and material could only prevent formation of bony bridge in small defect of growth plate and lacked ability of regenerative repair.
骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质，因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨，在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
目的通过引导性骨再生和组织工程软骨移植研究长骨骨缺损的修复机制。
Objective Study the mechanism of the healing of bone defect after transplantation of the tissue-engineered cartilage into the bone defects and with guided bone regeneration tubes.
比较结果显示，COL - HA生物支架材料相对于COL生物支架材料更适合用于软骨下骨或骨组织缺损的修复。
The results showed that COL-HA scaffolds were more suitable for the subchondral bone or bone defects repair than the COL scaffolds.
比较结果显示，COL - HA生物支架材料相对于COL生物支架材料更适合用于软骨下骨或骨组织缺损的修复。
The results showed that COL-HA scaffolds were more suitable for the subchondral bone or bone defects repair than the COL scaffolds.
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