目的探讨慢性马兜铃酸肾病的主要中医证候。
Objective To discuss the main symptoms and signs of chronic aristolochine nephropathy (CAN).
目的：对红金耳环中马兜铃酸A进行定量分析。
Objective:To analyse aristolochic acid A in Asarum petelotii O.
方法：用高效液相测定细辛不同部位马兜铃酸A的含量。
METHODS:HPLC method was used to determine aristolochic acid A content content in different parts of Herba Asari.
马兜铃酸有时会用于草药，主要用于治疗关节炎和痛风等病症。
Aristolochic acids are sometimes used in herbal medicines to treat conditions like arthritis and gout.
近年来，人们发现马兜铃酸是一种对人和动物都有致突变性的强致癌剂。
It is a potent carcinogens that has been found to be mutagenic in humans and animals for several years.
结果：马兜铃酸具有肾毒性、消化道毒性、致癌性、致突变性和基因毒性。
RESULTS: Aristolochic acid has nephrotoxicity, alimentary canal toxicity, carcinogenicity, mutagenicity and genotoxicity.
由于青蒿素抗体活性比马兜铃酸抗体活性强，因此检测出的青蒿素极限浓度较低。
The sensitivity of detecting Artemisinin is higher due to its antibody is more active than that of Aristolochic acid antibody.
方法回顾分析102例慢性马兜铃酸肾病患者中4例伴发泌尿系肿瘤患者的临床资料。
Methods the clinical data of urothelial carcinoma were analyzed in 4 cases among 102 patients with CAAN.
对马兜铃酸类的结构、检测方法、临床应用及其毒副作用进行了分析，并对马兜铃酸肾病进行了讨论。
This paper has studied the structure, method of measurement and clinical application of Aristolochic acids, and also discussed the aristolochic acid nephropathy(AAN).
在之前的研究中，我们发现马兜铃酸是一种强致突变剂，对小鼠淋巴瘤细胞有显著的细胞毒性和致突变作用。
In the previous study, we have found that AA is a potent mutagen which can induce significant cytotoxic and mutagenic effects on mouse lymphoma cells.
结论2005年版的《中国药典》将细辛药用部位由全草改为根茎是合理的，穴贴定喘膏未检出马兜铃酸a。
CONCLUSION it is reasonable that the 2005 edition of Chinese Pharmacopoeia specifies that the medicinal part of Herba cum Radice Asari is...
结论2005年版的《中国药典》将细辛药用部位由全草改为根茎是合理的，穴贴定喘膏未检出马兜铃酸a。
CONCLUSION it is reasonable that the 2005 edition of Chinese Pharmacopoeia specifies that the medicinal part of Herba cum Radice Asari is...
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