染色质由卷曲的DNA、组蛋白和非组蛋白组成。
Chromatin consists of coiled DNA bound to basic proteins called histones and non-histone proteins.
细胞的分化是一个动态的过程，带动激活和抑制特定的基因组，基因组转录活性和非活性染色质域的划分。
Cellular differentiation is a dynamic process driven by activation and repression of specific sets of genes, partitioning the genome into transcriptionally active and inactive chromatin domains.
操作上讲，修饰功能或者通过中断染色质接触或通过影响非组蛋白蛋白质招募到染色质上。
Operationally, modifications function either by disrupting chromatin contacts or by affecting the recruitment of nonhistone proteins to chromatin.
操作上讲，修饰功能或者通过中断染色质接触或通过影响非组蛋白蛋白质招募到染色质上。
Operationally, modifications function either by disrupting chromatin contacts or by affecting the recruitment of nonhistone proteins to chromatin.
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