• 如同阿尔茨海默病鼠,增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。

    As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.

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  • 实验表明大多数水解单宁具有很高的抗氧化活性,而乙酰化的黄酮甙抗氧化活性很低。

    Hydrolysable tannins showed much more effective antioxidant activity in DPPH assay while acetylated kaempferol glycosides displayed very low activity.

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  • 我们认为姜黄素的抗肿瘤作用,与其HAT抑制活性及对组蛋白乙酰化的诱导作用关系不大。

    We believe that the effect of HAT inhibition and induction of histone hyperacetylation of curcumin plays little role in its anti-cancer effect.

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  • 在2007年5月10日的自然杂志中,他们报道了一种促进组蛋白乙酰化的药物,它能增强阿耳茨海默氏病模型老鼠的学习和记忆能力。

    In the 10 May 2007 issue of Nature, they reported that a drug that promotes histone acetylation improved learning and memory in a mouse model of Alzheimer's disease.

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  • 对部分稀土离子参与下LeuRS催化的的氨酰化反应表观稳态动力学性质进行了研究。

    The apparent steady state kinetics of the aminoacylation reaction catalyzed by LeuRS at the participation of some RE 3+ was studied.

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  • 高脂肪组产的子鼠的葡萄糖代谢基因有些表观改变,组蛋白乙酰化环节——能打开DNA环使基因转录更容易——是其中一处改变。

    The high-fat offspring also had epigenetic modifications to genes that regulate glucose metabolism.

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  • 基因“开关”涉及乙酰化作用,也就是将乙酰基群在染色质的DNA水平上引入到分子中,由此完成基因转录。

    The genetic switch involves acetylation, the introduction of an acetyl group into a molecule at the DNA level of chromatin resulting in genetic transcription.

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  • 下面的视频是关于在癌症细胞里的常规基因表达是如何进行组蛋白乙酰化作用(acetylationofhistone)的。

    Here's a video that animates the acetylation of histone proteins in the regulation of gene expression in cancer cells.

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  • 反应在常温下进行,乙酰化产物的产率和质量与原方法相当。

    The reaction proceeds at room temperature and the quality and yield of acetylate are comparison with ordinary method.

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  • 其他的工作集中在组蛋白乙酰化,这种化学修饰可以使DNA从组蛋白缠绕中解离出来,产生基因活性。

    Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.

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  • 结论6APA生产中使用新的固定化青霉素酰化酶反应器将提高6 APA的收率,减少固定化青霉素酰化酶的损耗。

    Conclusions the usage of the new immobilized penicillin acylase reactor in the 6-apa production will result in a higher yield of 6-apa and lower loss of immobilized penicillin acylase.

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  • 现已确认,乙酰化甘露聚糖在增强人们的免疫系统方面极为有效。

    Acemannan has been recognized as extremely effective at boosting people's immune system.

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  • 乙酰化反应使组蛋白让DNA解螺旋,允许了基因的表达发生,因此抑制乙酰化反应将从总体上降低基因的表达。

    Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.

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  • 最后,科学家将剩余的氨基进行乙酰化,这保证了复杂粒子不会受到表面电荷影响。

    Finally, the remaining amine groups are acetylated to ensure that the complex particles do not bear any surface charges.

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  • 通过成本比较,认为丙酰氯是合适的酰化剂。

    The propionyl chloride was found to be the appropriate acylating agent in terms of the cost.

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  • 随着研究的深入,发现蛋白质乙酰化状态对细胞因子的分泌、NO的产生等方面均有较大的影响。

    With in-depth study, we found that protein acetylation have great influence in the secretion of cytokines, generation of NO and so on.

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  • 报道了由苯酚经过乙酰化、肟化、重排反应合成扑热息痛的一种新方法。

    This paper reports a new process of synthesizing paracetamol from phenol by acetylization, oximation and Beckmann rearrangement.

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  • 本文研究了交联淀粉和乙酰化淀粉的制备工艺。

    The technology of preparing crosslinking starch and acetylated starch is studied in this paper.

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  • 目前,合成过程的中间监测方法主要集中在胺酰化及脱保护反应,而对于中间体一活化酯的反应进程没有监测方法。

    Currently, the reaction progress monitoring focuses on amide acylation and deprotection reaction, while there is no method for the reaction progress of the intermediate-active esters.

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  • 目的制备盐酸他克林(THA)的酰化前体药物以提高其透过血脑屏障(BBB)的能力。

    Aim to synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).

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  • 该单克隆抗体用合成的含乙酰化赖氨酸的肽段库免疫动物制备。

    Monoclonal antibody is produced by immunizing animals with a synthetic acetylated lysine-containing peptide.

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  • 结果表明:乙酸木质素具有典型的聚多元醇结构,虽然有部分被乙酰化,但它具有很好的溶解性;

    The results showed that AAL had the typical structure of polyol and good dissolvability, though a part of AAL was acetylated.

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  • 组蛋白尾端不同的化学修饰往往和基因的表达调控有着密切的关系,乙酰化就是常见的一种修饰形式。

    Gene expression is often closely related to the different chemical modification ends of protein, acetylation is a kind of common form of modification.

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  • 本文研究了以碳酸镍合成硼酰化镍的新方法。

    This paper reports a new synthetic method of nickel borate acylate.

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  • 这表明酶基酰化酶构象的完整性是酶具有催化活力的基础。

    This suggests that conformational integrity of aminoacylase appears to be essential for its catalytic activity.

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  • 人们很早就注意到,真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。

    It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.

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  • 乙酰化使硬质纤维板具较大的尺寸稳定性。

    The acetylation imparts greater stability to the dimensions of the hardboard.

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  • 乙酰化使硬质纤维板具较大的尺寸稳定性。

    The acetylation imparts greater stability to the dimensions of the hardboard.

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