利用连锁不平衡进行QTL精细作图是QTL定位研究的一个新热点。
Fine mapping of QTL using linkage disequilibrium becomes more and more popular.
连锁不平衡分析是对基因(或已定位的高分辨率QTL)的功能进行鉴定的有效方法。
Linkage disequilibrium analysis is a effective way to identify the function of the of the gene (or targeted high-resolution QTL).
传递不平衡检验是基于家系检测疾病位点与标记位点之间连锁与连锁不平衡的经典分析方法。
The haplotype-based haplotype relative risk( HHRR ) and transmission disequilibrium test ( TDT ) methods were used to analyze the association between DRD4 and ADHD.
在关联分析中，SNP的最终价值很大程度上取决于其在人群中的频率分布以及彼此之间的连锁不平衡状况。
The ultimate value of SNPs for linkage and association mapping depends in part on the allele frequencies of the markers and inter-marker linkage disequilibrium across populations.
结论在染色体异常核型中，均有不同程度的基因缺失，造成基因连锁的不平衡，因而出现一些临床效应。
Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.
结论在染色体异常核型中，均有不同程度的基因缺失，造成基因连锁的不平衡，因而出现一些临床效应。
Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.
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