端粒酶在胃印戒细胞癌组织内过表达。
Telomerase was over expression in gastric signet-ring cell carcinoma.
EGFR过表达的肿瘤放疗效果差，易复发，预后不良。
EGFR overexpression is associated with more aggressive tumors, resistance to ionizing radiation, easy recurrence and poor prognosis.
目的：探讨血管内皮生长因子在乳癌中过表达的临床意义。
Objective: To investigate the clinical significance of VEGF expression in human breast cancer.
但重要的是，脑肿瘤干细胞中这些分子呈现显著的过表达。
Importantly, a significant over-expression of these molecules were found in the brain tumor stem cells.
P 27过表达与癌细胞恶性生物学行为和死亡率呈负相关。
The P27 over expression was not related to the cancer cell biological malignant behavior and death rate.
P27过表达与癌细胞恶性生物学行为和死亡率呈负相关。
P27 over expression was not related to the cancer cell biological malignant behavior as regards death rate.
表达阵列分析显示过表达CT120B诱导的基因表达谱变化；
The differential gene expression induced by overexpressed CT120B was investigated using Atlas cDNA expression array.
STK15过表达诱导中心体数目增多，异倍体形成和细胞转化。
Overexpression of STK15 induces increased Numbers of centrosome, aneuploidy, and transformation of the cells.
结论TIMP - 1过表达可通过增强炎症加重肾小管间质损伤。
Conclusions Overexpression of TIMP-1 exacerbates renal tubulointerstitial injury by enhancing inflammation.
基因无效或过表达的生理学模型将成为珍贵的检测这些生物新发现的工具。
Physiological models with invalidated or over-expressed genes will be precious tools to check these new biological discoveries.
EGFR蛋白过表达和EGFR拷贝数改变的肿瘤内异质性无统计学意义。
Intratumoral heterogeneity of EGFR protein overexpression and EGFR copy number alteration was not significant.
在肿瘤发生中，PIAS蛋白的过表达能抑制癌细胞的增殖并诱导其凋亡。
In tumor, overexpression of PIAS can inhibit the proliferation of cancer cells and induce cell apoptosis.
结论腺病毒介导的人诱导型HSP70的过表达抑制了低钾诱导的CGN凋亡。
Conclusion Adenovirus-mediated human inducible HSP70 overexpression inhibits apoptosis of CGN induced by low potassium.
梗死7天后，组成性过表达A 20的小鼠心脏梗死范围减少、心功能有所改善。
Constitutive overexpression of A20 in the murine heart resulted in attenuated infarct size and improved cardiac function 7 days after myocardial infarction.
结论-继发于TNF过表达的心脏功能障碍与心肌腺苷和AR水平的显著改变有关。
Conclusions - Cardiac dysfunction secondary to the overexpression of TNF is associated with marked alterations in myocardial levels of adenosine and ARs.
在本研究中，我们检验了心脏特异型过表达A 20可以保护心脏免于发生心肌梗死。
In the present study, we tested the hypothesis that cardiac-specific overexpression of A20 could protect the heart from myocardial infarction.
结论：VEGF过表达提示患者预后不良，检测VEGF对化疗方案选择有指导意义。
Conclusion:The overexperssion of VEGF may be predict poor prognosis and VEGF examined is helpful for chemotherapy plan of breast cancer.
研究人员发现WIP1的过表达与某些人类肿瘤的不良预后和低存活率相关(7,8)。
Researchers have shown that increased expression of WIP1 is associated with poor prognosis and lower survival rate in some human cancers (7, 8).
表皮生长因子受体（EGFR）及其配体的过表达与疾病的迅速进展和对化疗的耐药有密切的联系。
The overexpression of the epidermal growth factor receptor and its ligands correlates with rapidly progressive disease and resistance to chemotherapy.
在非侵袭性癌细胞中过表达MAGL重现这一脂肪酸网络，并增加其被MAGL抑制剂逆转的致病性。
Overexpression of MAGL in nonaggressive cancer cells recapitulates this fatty acid network and increases their pathogenicity phenotypes that are reversed by an MAGL inhibitor.
背景：脂肪酸合成酶(FASN)过表达参与了前列腺癌的发生。我们直接研究FASN的致癌潜能。
Background: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.
像老年痴呆症这样的疾病会影响NR2B的表达，而可以使该基因过表达的药物能够抵消这些疾病的影响。
Diseases like Alzheimer's affect NR2B expression, so a drug that causes the gene to over-express could counteract the affects of the disease.
它在鼻咽癌细胞和组织中表达明显下调，过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
细胞周期蛋白d1在癌症中经常过表达，可引起其过表达的因素很多，包括增加转录，翻译和蛋白质的稳定性。
Cyclin D1 is frequently over-expressed in cancers and its overexpression can be attributed to many factors including increased transcription, translation, and protein stability.
同样，在公开的乳腺癌基因表达数据库中，SF3B 3过表达与总生存率显著相关，SF 3b1则无此作用。
Similarly, in publicly available breast cancer gene expression data sets, overexpression of SF3B3, but not SF3B1, was significantly correlated with overall survival.
EBL的发生与突变的P53蛋白过表达有重要关系，携带P53突变株的B淋巴细胞可能是形成肿瘤的靶细胞。
The positive cells expression of P53 had an important relation to the appearance of EBL. B cells with P53 mutation strain might be a target cell to format tumors.
转录靶向性利用一些肿瘤过表达某些特定基因，所以使用此基因特异性启动子可以驱动治疗基因达到靶向性治疗目的。
Transcriptional targeting takes advantage of the fact that some cancer cells express a subset of exclusive genes, and USES these cancer-specific promoters to express the desired transgenes.
这只转基因鼠小弟名叫荷比-杰。通过使控制其神经元传输的基因过表达，它走迷宫和记忆玩具的能力得到了极大的提升。
The genetically engineered rat, Hobbie-J, over-expresses a gene that regulates neuron communication, greatly enhancing the rat's ability to navigate mazes and remember toys.
这只转基因鼠小弟名叫荷比-杰。通过使控制其神经元传输的基因过表达，它走迷宫和记忆玩具的能力得到了极大的提升。
The genetically engineered rat, Hobbie-J, over-expresses a gene that regulates neuron communication, greatly enhancing the rat's ability to navigate mazes and remember toys.
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