目的探讨超抗原诱导T细胞无能的分子机制。
Aim To explore the molecular mechanism of t cell anergy induced by superantigen SEA.
此外，表皮剥脱毒素还可能作为超抗原参与发病。
In addition, ETs may act as a superantigen in the pathogenesis of SSSS.
但最近的研究表明，超抗原激活t细胞还有一条旁路信号途径。
However, recent research shows that SAgs also activate an alternative signaling pathway in t cells.
细胞因子-超抗原融合蛋白对于实体肿瘤有着很明显的杀伤作用。
The cell factor-superantigen fusion protein has an obvious killing effect on the solid tumor.
结论：ICAM1相关小分子肽可望降低超抗原介导的皮肤炎症反应。
Conclusion: ICAM 1 related small peptide could reduce skin inflammation mediated by superantigens.
鉴于超抗原的这种特性，医学上已成功将其用于癌症和病毒病的辅助治疗。
Due to this character, it has be successfully applied to the assistant treatment of cancer and virosis.
结论：ICAM - 1相关小分子肽可望降低超抗原介导的皮肤炎症反应。
Conclusion: ICAM-1 related small peptide could reduce skin inflammation mediated by superantigens.
目的探讨链球菌超抗原与银屑病的关系，揭示银屑病患者外周血T细胞的特殊活性。
Objective To study the relationship between streptococcal superantigen and psoriasis and reveal the specific activity of psoriatic peripheral blood T lymphocytes.
体外刺激脾淋巴细胞增殖实验以及体外肿瘤细胞增殖抑制试验表明该蛋白具备良好的超抗原活性。
The typical superantigen activity of the purified protein was proved by lymphocyte proliferation test and tumor growth inhibition test.
体外刺激脾淋巴细胞增殖实验以及体外肿瘤细胞增殖抑制试验表明该蛋白具备良好的超抗原活性。
The total yield was 23% with the purity of 90%. The typical superantigen activity of the purified protein was proved by lymphocyte proliferation test and tumor growth inhibition test.
结果SED的空间结构与其它肠毒素超抗原相似，具有两个结构域：氨基末端结构域和羧基末端结构域。
Results the three dimensional structure of sed, similar to that of other enterotoxin superantigens, was composed of two domains: amino terminal domain and carboxyl terminal domain.
在兽医科学上，超抗原有望在兽医病理学、兽医药理学、兽医临床治疗和兽医预防方面得到广泛的应用。
In veterinary science, it will be going to be widely applied to veterinary pathology, veterinary pharmacology, veterinary clinical treatment and prevention.
超抗原以极低的浓度就能引起机体免疫细胞、细胞因子和抗体的巨大变化，引起机体一系列病理生理过程。
Superantigen in very light concentration can cause an enormous change of immunocytes, cytokines and antibody, cause a series of pathological and physiological change in the body.
本研究为今后选择合适的辅助分子与合成肽技术共同组建一种有效的探找超抗原T细胞表位的方法奠定了基础。
This study paved the way for choosing a reasonable assistant molecule with the synthetic peptide technique to establish a new method for localizing t cell epitopes on superantigens.
细胞因子-超抗原融合蛋白实际上是代替现有技术的抗体的，也具有靶向作用，是区别于抗体的新的可期待的药物。
The superantigen fusion protein cell factor is actually a substitute for the antigen in the prior art, has a targeting function and is a new prospective medicament different from the antigen.
细胞因子-超抗原融合蛋白实际上是代替现有技术的抗体的，也具有靶向作用，是区别于抗体的新的可期待的药物。
The superantigen fusion protein cell factor is actually a substitute for the antigen in the prior art, has a targeting function and is a new prospective medicament different from the antigen.
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