用高效液相色谱法测定补骨脂素的含量。
文中综述了补骨脂素的抗肿瘤机理及应用研究展望。
This paper summarized the antitumor mechanism and application prospect of Psoralen.
光毒物质8-甲氧补骨脂素同时引起局部淋巴结增殖和耳肿胀反应。
But 8-methoxypsoralen, a phototoxic substance, induced both lymph node hyperplasia and ear swelling.
目的：建立甲氧补骨脂素搽剂中8-甲氧补骨脂素的含量测定方法。
OBJECTIVE:To establish a assay method for 8 Methoxsalen in Methoxsalen.
结论8-甲氧补骨脂素乳膏皮肤局部用药对实验动物具有较好的安全性。
Conclusion : Topical use of 8-methoxypsoralen cream on the animal skin is safe.
近年来研究发现，某些中草药如姜黄素、黄柏、补骨脂素等具有一定的光敏活性作用。
Recent research has showed that some Chinese herds such as curcumin, cortex phellodendri, psoralen et al, have photodynamic reaction.
比起局部用补骨脂素或口服后再照UVA，窄谱紫外线有较好的恢复色素的效果和安全性。
Narrow-band ultraviolet B (UVB) has better overall repigmentation rates and safety profile than either topical or oral psoralens and ultraviolet A (PUVA).
目的：研究8-甲氧基补骨脂素（8-MOP）对粘液表皮样癌细胞（MEC-1）的抑制作用。
Objective:To study the inhibitory effects of 8-MOP on mucoepidermoid carcinoma MEC-1 cells.
目的制备外用的载有补骨脂素的PLGA纳米粒，为临床上改进PUVA疗法降低其毒副作用奠定基础。
OBJECTIVE to develope and characterize psoralen loaded PLGA nanoparticles for topical formulation, with the final goal of reducing the toxicity and improving the efficacy of PUVA therapy.
本研究的目的是观察预激态补骨脂素对K5 6 2细胞增殖的影响，为补骨脂素的临床应用提供实验依据。
The objective was to observe the influence of previously activated psoralens on the proliferation of K562 cells, and to provide laboratory data for its clinical usage.
结果表明，补骨脂素对酪氨酸酶有明显的激活作用，但是不随浓度的增加呈线性变化，与助剂复配的协同效应显著。
It was indicated that psoralen had an obvious activation on tyrosinase activity and synergistic effect was significant, but the relationship with concentration was nonlinear.
结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。
CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.
本实验对生物素化补骨脂素标记核酸的条件和效果进行了研究，发现该试剂不仅能标记双链dna、单链dna，更重要的是可以直接标记RNA及寡核苷酸。
We have systematically studied the relations between the probe labelling effects and conditions, and found that it not only can label dsDNA, ssDNA, but also RNA and oligonucleotide.
本实验对生物素化补骨脂素标记核酸的条件和效果进行了研究，发现该试剂不仅能标记双链dna、单链dna，更重要的是可以直接标记RNA及寡核苷酸。
We have systematically studied the relations between the probe labelling effects and conditions, and found that it not only can label dsDNA, ssDNA, but also RNA and oligonucleotide.
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