该技术基于β-葡糖醛酸糖苷酶（一种来自大肠杆菌的酶）。
The technique is based on beta-glucuronidase, an enzyme from the bacterium Escherichia coli.
结论染料木黄酮首过代谢突出，血浆中药物主要以葡糖醛酸结合形式存在。
Conclusion Due to significant first pass metabolism, the drug was mainly existed in the form of glucuronidated genistein in the plasma.
目的为建立能稳定表达人葡糖醛酸转移酶UDPGT1A9蛋白的CHL UDPGT1A9转基因细胞系，并鉴定其对药物的葡糖醛酸缀合活性。
AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.
目的为建立能稳定表达人葡糖醛酸转移酶UDPGT1A9蛋白的CHL UDPGT1A9转基因细胞系，并鉴定其对药物的葡糖醛酸缀合活性。
AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.
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