药代动力学参数为临床用药提供了依据。
大多数药代动力学参数的个体间差异大于8倍。
The individual variation inmost of pharmacokinetic parameters is more than 8 folds.
结论：国产和进口格列吡嗪片的药代动力学参数无差异。
CONCLUSION: There were no differences in pharmacokinetic parameters between the domestic and the imported glipizide tablets.
CYP3A酶活性通过咪达唑伦药代动力学参数进行反应。
The activity of CYP3A was reflected by the pharmacokinetics of midazolam.
结果得到血管内给药二室模型药代动力学参数估算的电子计算机程序。
Results An electronic computer program for pharmacokenetic parameter estimation was gained, and was applied to the pharmacokenetic parameter estimation.
结论利用SAEM算法估计群体药代动力学参数是一个比较好的方法。
Conclusion the SAEM algorithm is an efficient fitting method for the population pharmacokinetics parameter estimation.
结论：双氯芬酸钠肠溶片在我国正常志愿者的药代动力学参数与国外的相似。
Conclusion the pharmacokinetic parameters of diclofenac tablets in Chinese young volunteer is similar to that other report.
目的了解去甲万古霉素在脑膜炎模型中的脑脊液透过率及其他药代动力学参数。
Objective it is to investigate the filterability of Norvancomycin in cerebrospinal fluid and other pharmacokinetic indexes in meningitis models of rabbits.
但是，辛伐他汀及其主要代谢产物辛伐他汀酸的药代动力学参数没有出现统计学上的差异。
However, no significant discrepancy was detected in the pharmacokinetics parameters of simvastatin and its main metabolite simvastatin aicd.
方法：采用LC/MS/MS（APCI源）测定地洛他定的血浆浓度，并计算药代动力学参数。
METHODS: The concentrations of desloratadine were determined by LC/MS/MS with APCI and the pharmacokinetic parameters were calculated.
结论靶控效应室浓度输注异丙酚时，效应室浓度与BIS的变化不完全一致可能是药代动力学参数造成的差异。
Conclusion The inconsistency of BIS with effect-site concentration during TCI of propofol may result from its pharmacokinetic parameters.
结论根据药效学参数并结合药代动力学参数，确定合适的给药间隔时间，可以安全、有效、经济地使用抗菌药物。
Conclusion Basing pharmacodynamic and pharmacokinetic parameters, to confirm appropriate interval time using medicine may use antimicrobials safely, rationally and economically.
结论老年心衰病人的个体药代动力学参数波动范围大，个体差异更为突出，临床应在血药浓度监测的基础上实行最佳个体化给药。
Conclusions there is a significant individual variation in the pharmacokinetic parameters, therefore, the dose should be individualized on the basis of blood drug concentration monitoring.
有了强大的单位管理工具，用户可以指定输出的药代动力学参数的单位，以及投入的时间和来自大规模的测量单位名单中的集结单位。
With a powerful unit management tool, user can specify the output pharmacokinetic parameter units as well as input time and concentration units from an extensive list of measurement units.
大多数药物的药代动力学作用可用下列参数加以归纳。
The pharmacokinetic behavior of most drugs can be summarized by the following parameters.
大多数药物的药代动力学作用可用下列参数加以归纳。
The pharmacokinetic behavior of most drugs can be summarized by the following parameters.
应用推荐