目的用高精度散射光度滴定法测定苯妥英钠。
Aim to determine phenytoin sodium by a highly accurate nephelometric titration.
目的观察苯妥英钠对大鼠实验性胃溃疡的保护作用。
Objective To observe the protective effect of PHT on experimental gastric ulcer.
目的:观察长期服用苯妥英钠的癫患者周围神经损害。
Objectives:To explore the neuroelectropysiological features of patients with epilepsy in long-term taking dilantin.
应用苯妥英钠治疗癫痫的病人一般不需加用甲状腺素。
To the patients using phenytoin sodium, it normally does not need to add thyroxin.
方法:测定29例单用苯妥英钠病人的血清甲状腺素。
MRTHODS:In this study, the thyroid hormone level was tested in 29 patients treated with phenytoin sodium only.
目的研究血液灌流对严重苯妥英钠中毒患者的治疗作用。
Objective to study the effects of hemoperfusion on the patients with severe phenytoin sodium intoxication.
目的:考察苯妥英钠中毒浓度与下肢运动障碍间的相关性。
Objective: To study the correlation between phenytoin poisoning and the impediment to leg activity.
该结果提示苯妥英钠对细胞核遗传物质具有一定损伤作用。
It suggests phenytoin sodium has some injury to caryon genetic material.
建立了以毛细管区带电泳测定血浆中苯妥英钠含量的方法。
A method to determine sodium phenytoin in plasma by high performance capillary zone electrophoresis (CZE) has been established.
目的探讨癫痫病人应用苯妥英钠(PH)疗的最佳有效血药浓度。
Objective To find out the best and effective serum concentration of DPH for patients with epilepsy.
本文采用一阶导数紫外分光光度法直接测定注射用苯妥英钠的含量。
The Content of phenytoin sodium (for injection) was determined directly by the first order derivative spectrophotometry.
目的对苯妥英钠进行药物动力学研究,制定苯妥英钠个体化给药方案。
Objective Making researches into pharmacokinetics for phenytoin and laying down individuation drug delivery scheme for phenytoin sodium.
本文介绍了用放射免疫法测定82例癫痫病人血中苯妥英钠浓度的结果。
This paper presents the results of measurements of blood diphenylhydantoin (DPH) concentration in 82 epileptic patients by radioimmunoassay.
目的研究用HPLC和FPIA两种方法测定苯妥英钠血药浓度的相关性。
OBJECTIVE to study the relativity between serum phenytoin concentrations determined by HPLC and FPIA.
苯妥英钠组测试成绩提高较慢(P<0.05),与NS组比较无明显差异。
The performance record of TPM group has been elevated slowly (P>0.05) , and is worse than NS group.
本文报告不同浓度苯妥英钠体外培养人外周血淋巴细胞微核及染色体研究结果。
It reported the results of study on human peripheral blood lymphocyte micronucleus and chromosome cultured in vitro with different concentration of phenytoin sodium.
本文对42例患者血清的苯妥英钠浓度及17例唾液浓度用放免测定法进行监测。
The measurement of DPH concentration both in serum for 42 patients and in saliva for 17 patients was performed by the use of the radioimmunoassay.
目的建立注射用磷苯妥英钠的含量和有关物质的分析方法,用于该产品的质量控制。
OBJECTIVE to establish a method of quality analysis of fosphenytoin sodium injection, which is applied for quality control.
一例长期服用较大剂量苯妥英钠的癫痫患者出现了脑病、小脑变性、周围神经病和肌病。
A patient with generalized seizure disorder who took the larger dose of phenytoin sodium over a long period of time, showed encephalopathy, cerebellar ataxia, peripheral neuropathy and myopathy.
结论丙戊酸钠、苯妥英钠治疗癫痫全面性强直阵挛发作疗效肯定,但苯妥英钠不良反应多。
Conclusion Sodium valproate and phenytion sodium have the certain clinical efficacy in treatment of generalized tonic-clonic seizure. But phenytion sodium has the more and worse untoward reaction.
方法对69例延迟愈合伤口患者接受苯妥英钠治疗的疗效、副作用、住院时间等情况进行回顾分析。
Methods the therapeutic effect, side effect and length of stay about 69 cases with delayed healing wound were retrospectively analyzed.
结果苯妥英钠高、低剂量组均显示出保护作用(P<0.05),但高剂量组的保护作用不如低剂量组的明显。
Results PHT showed protective effect in both high and low dose groups(P<0.05), but low dose group showed better protective effect than high dose group.
结论慢性应激对大鼠血清NO含量无影响,但可诱导大鼠海马NO含量升高,苯妥英钠可以抑制慢性应激所致海马NO的过度生成。
Conclusions The exposure to chronic stress did not cause significant change of no levels in serum of rats, but induced excessive production of no in hippocampus, which could be inhibited by phenytoin.
苯妥英钠对缺血性脑损伤的神经保护作用与其能抑制自由基形成,减轻自由基介导的毒性,抗脂质过氧化反应以及扩张血管,增加局部脑血流量有关。
Phenytoin sodium may protect brain tissues from cerebral ischemic injury by inhibiting formation of free radical, anti-lipid peroxidation and improving regional cerebral blood flow.
方法:采用荧光偏振免疫法对2 6例服用苯妥英钠、74例服用卡马西平、14 4例服用丙戊酸钠的患者血药浓度监测结果及临床疗效分析、评价。
Method: The serum concentration of oral phenytoin, carbamazepine and valproic acid were determined in 26,74 and 144 epileptic patients by fluorescence polarization immunoassay, respectively.
方法:采用荧光偏振免疫法对2 6例服用苯妥英钠、74例服用卡马西平、14 4例服用丙戊酸钠的患者血药浓度监测结果及临床疗效分析、评价。
Method: The serum concentration of oral phenytoin, carbamazepine and valproic acid were determined in 26,74 and 144 epileptic patients by fluorescence polarization immunoassay, respectively.
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