前言：目的：建立SD大鼠苯中毒模型。
Objective: to establish a model of benzene toxicosis in rats.
目的探讨慢性苯中毒患者骨髓细胞的一些形态特征。
Objective To explore morphological features of bone marrow cells in chronic benzene intoxication cases.
目的筛选与苯中毒有关的DNA复制及损伤修复基因。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
结果：模型鼠血液学变化符合人苯中毒国家诊断标准变化趋势。
Results: the changes of hematological parameters of these animals corresponded with the national diagnostic criteria of benzene toxicosis in human body.
结论联合治疗苯中毒取得满意疗效，是值得推广的一种有效治疗方法。
Conclusion the combined treatment could reach the satisfactory effect and might be an effective method extended in clinic.
GSTP1基因多态与慢性苯中毒遗传易感性的关系仍需进一步研究。
Further studies should be needed on the association between the genetic polymorphisms in GSTP1 and the risk of BP.
方法对46例重度苯中毒进行骨髓穿刺，取骨髓液及活体组织进行研究。
Methods Bone marrow smear and biopsy in 46 benzene poisoning cases were analyzed.
目的：探讨南瓜提取物对慢性苯中毒所造成的机体抗氧化系统损伤的拮抗作用。
Objective:To explore the effects of Pumpkin Extracts(PKE)on oxidative damage effect of chronic benzene poisoning in mice.
目的研究环境暴露因素与毒物代谢酶基因多态性对发生慢性苯中毒危险性的影响。
Objective to explore the effects of interaction between environmental exposure factors and genetic polymorphism in toxicant metabolizing enzymes on risk of occupational chronic benzene poisoning.
苯中毒患者的骨髓涂片中粒红比值、巨核细胞数量随着骨髓增生程度降低而降低。
Bone marrow hypoplasia coincided with the reduction of the ratios of granulocytes to erythrocytes as well as the megakaryocytes count. Conclusion Bone marrow biopsy and smear examination are valu…
探讨谷胱甘肽硫转移酶（GST）基因多态与慢性苯中毒患者血清中必需元素的关系。
To study the relationship between essential elements and GST genetic polymorphisms in patients with chronic benzene poisoning.
[目的]探讨谷胱甘肽硫转移酶(GST)基因多态与慢性苯中毒患者血清中必需元素的关系。
[Objective] To study the relationship between essential elements and GST genetic polymorphisms in patients with chronic benzene poisoning.
结论：苯代谢产物诱导的造血细胞凋亡和坏死可能是苯中毒导致的造血功能障碍的主要机制之一。
Conclusion Metabolites of benzene can induced hematopoietic cell apoptosis and necrosis, and give rise to aplastic anemia.
且影响慢性苯中毒患者和铅中毒观察对象生存质量的因素是多方面的，其中疾病是一个重要的因素。
There were many factors influencing the QOL of the chronic benzene poisoning patients and the chronic lead poisoning patients, and the disease was one of the important factors.
目的应用中毒严重程度护理综合评分工具，对苯中毒患者给予合理护理量，以提高护理工作的质量。
Objective with the tool of nursing comprehensive score for grading the severity of poisoning, to evaluate the required quantity of nursing to the patients with severe benzene poisoning.
方法采用病例-对照研究，选择152名苯中毒工人为病例组，152名接触苯而无中毒表现的工人为对照组。
Methods A case control study was conducted. 152 BP patients and 152 workers occupationally exposed to benzene without poisoning manifestations were involved.
第三，要减少苯的接触，慢性苯中毒主要伤害人体的造血系统，引起白细胞，血小板数量的减少，诱发白血病。
Third, we must reduce benzene exposure, chronic benzene poisoning major harm to the human hematopoietic system, caused WBC, decrease in the number of platelets, induced leukemia.
结果联合治疗苯中毒中，再障2例均治愈，1例骨髓增生异常综合征(MDS)明显进步，1例急性造血停滞治愈。
Results 2 cases of aplastic anemia were cured and 1 case MDS was improved and 1 cured of stasis to produce blood.
目的探讨DNA修复基因XRCC1、XRCC3多态性与慢性苯中毒遗传易感性的关联及其与慢性苯中毒潜伏期的关系。
Objective To explore the association between genetic polymorphisms of DNA repair genes XRCC1 , XRCC3 and susceptibility to chronic benzene poisoning.
结论EPHX1基因多态性可能与慢性苯中毒发生危险性相关，而EPHX2基因多态与慢性苯中毒易感性关系需进一步研究。
Conclusions genetic polymorphisms in EPHX1 may be associated with the risk of CBP, and further research is needed for the association between genetic polymorphisms in EPHX2 and susceptibility to CBP.
根据作业环境条件选择130名工人，分为对照组、低浓度接触组和高浓度接触组，同时将25名轻度苯中毒工人列为中毒组。
According to the working environment 130 workers were divided into control group, low con centration group, and high concentration group.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达，为进一步筛选苯中毒生物标志物提供了依据。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达，为进一步筛选苯中毒生物标志物提供了依据。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
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