结论舒林酸对FAP疗效显著,可使腺瘤明显消退。
Conclusions The efficacy of sulindac is significant in regressing colonic adenomas of patients with FAP.
目的评价舒林酸治疗结直肠息肉的有效性和安全性。
Objective To assess the efficacy and safety of sulindac on colorectal polyps.
目的:观察新型非类固醇类抗炎药—舒林酸对实验性高钙尿症的防治作用,探讨其可能机制。
OBJECTIVE to observe the therapeutic effects of sulindac (a new type of NSAIDs) on experimental hypercalciuria and to clarify its pharmacological mechanism.
结果骨架材料的种类、型号及用量对舒林酸释放机制影响较大,填充剂对舒林酸释放有一定影响。
Result the sorts, model and amounts of matrix materials had remarkable influence on the release mechanism of sulindac from the matrix tablets, while the influence of the selected fillers was marginal.
结论:舒林酸可抑制结肠癌细胞株ht - 29生长,其机制可能与其阻止细胞周期的进展,诱导细胞凋亡有关。
Conclusions: Sulindac may inhibit the proliferation and induce apoptosis of colon cancer cell HT-29, and its mechanism probably relates to the progress of its prevention on cell cycle.
结论舒林酸的硫化代谢产物能够显著抑制血管内皮细胞的增殖活性,改变细胞的周期分布,使细胞阻滞于G 2期,并可能在此期诱导其凋亡。
Conclusions Sulfide can significantly reduce the proliferation of ECV304, change the cell cycle distribution and arrest cells in G2-M phase where apoptosis may be induced.
结论舒林酸的硫化代谢产物能够显著抑制血管内皮细胞的增殖活性,改变细胞的周期分布,使细胞阻滞于G 2期,并可能在此期诱导其凋亡。
Conclusions Sulfide can significantly reduce the proliferation of ECV304, change the cell cycle distribution and arrest cells in G2-M phase where apoptosis may be induced.
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