结论培养的细胞为大鼠肾小球系膜细胞。
Conclusion the cultured cells form the glomeruli of rats were glomerular mesangial cells.
方法：分离并培养大鼠原代肾小球系膜细胞。
目的研究氯通道阻滞剂对肾小球系膜细胞增殖的作用。
Aim To investigate effects of chloride channel blockers on proliferation of mesangial cells.
结论ALD通过调控细胞周期抑制肾小球系膜细胞增殖。
Conclusion ALD inhibits the proliferation of rat mesangial cells by regulating cell cycle.
因此TGP可以保护高糖诱导的肾小球系膜细胞氧化应激损伤。
Therefore we conclude that TGP could protect mesangial cells against oxidative stress induced by high glucose.
因此，抑制肾小球系膜细胞增殖是防治肾小球硬化的重要措施。
It is concluded that it is a key to treat the glomerular sclerosis by inhibiting the proliferation of mesangial cells.
目的：探讨尼卡地平对大鼠肾小球系膜细胞凋亡的影响及其分子机理。
Objective:To explore the effects of nicardipine on apoptosis of rat mesangial cells and its molecular mechanisms.
目的：探讨中药肾康注射液对脂多糖诱导肾小球系膜细胞增殖的影响。
Objective: To study the effect of Shenkang injection on the proliferation of human mesangial cell induced by LPS.
目的探讨醛固酮对大鼠肾小球系膜细胞结缔组织生长因子基因表达的影响。
To evaluate the effect of aldosterone on connective tissue growth factor mRNA expression in cultured rat mesangial cells.
目的探讨“延肾胶囊”对残肾肾小球系膜细胞凋亡及其细胞外基质代谢的影响。
Objective To elucidate the effect of Yan-Shen Capsule on glomerular mesangial cell apoptosis and extracellular matrix metabolism of remnant kidney.
目的观察缓激肽（BK）对高糖浓度下肾小球系膜细胞增殖和细胞外基质分泌的影响。
Objective To observe the effect of bradykinin(BK) on kidney mesangial cell multiplication and extracellular matrix secretion under high glucose environment.
目的：探讨肾康注射液与苯那普利对人肾小球系膜细胞（MC）增殖的不同抑制作用强度。
To explore the intensity of inhibitory function of Shenkang injection (SKI), a Chinese herbal recipe, and benazepril on the proliferation of human glomerular mesangial cell (MC).
结论：高糖可导致人肾小球系膜细胞ICAM - 1表达的增加，而茶多酚可有效干预此效应。
Conclusion: high glucose contributes to the increase of ICAM-1 expression in human mesangial cells. TPs can reduce high glucose-induced expression of ICAM-1.
肾血宁胶囊能抑制肾小球系膜细胞的增殖，并通过下调FN在肾内的表达，抑制肾小球细胞外基质的积聚；
Shen-Xue-Ning capsule can inhibit mesentery cell hyperplasia and extracellular matrix collection of glomerular by regulating FN in kidney;
目的研究醛固酮(ald)及其受体拮抗剂螺内酯(SPI)对大鼠肾小球系膜细胞增殖和细胞周期的影响。
Aim to evaluate the effects of aldosterone (ald) and spironolactone (spi, one of the aldosterone receptor antagonists) on proliferation and cell cycle phase of cultured rat mesangial cells in vitro.
结论一定浓度的苦参素可以抑制肾小球纤维化，保护肾小球系膜细胞，而对系膜细胞的表型转化无明显作用。
Conclusion Certain concentration of oxymatrine can inhibit kidney fibrosis and protect mesangial cells, but have no effect on the phenotype of mesangial cells.
目的探讨人肾小球系膜细胞脂蛋白脂酶（LPL）的表达情况以及极低密度脂蛋白（VLDL）对其表达的影响。
Objective To study the expression of lipoprotein lipase(LPL) in human glomerular mesangial cells and the effect of very low-density lipoprotein(VLDL) on the expression of LPL.
目的：研究高糖对人肾小球系膜细胞丝裂原蛋白激酶（MAPK）活性的影响，探讨其在糖尿病肾病发病中的作用。
Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.
目的：探讨血小板活化因子(PAF)对肾小球系膜细胞(GMC)合成前列腺素e2 (PGE2)的影响及其意义。
OBJECTIVE to explore the effect and significance of platelet activating factor (PAF) on prostaglandin E2 (PGE2) synthesis in rat glomerular mesangial cell (GMC) in culture.
目的研究血小板衍生生长因子bb (PDGF - BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
Objective to investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB (PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.
肾小球系膜细胞(GMC)的增殖通过影响细胞外基质(ecm)的分泌和对肾小球毛细血管的机械损伤而在肾小球硬化过程中发挥着重要作用。
BackgroundThe GMC proliferation plays an important role in glomerular sclerosis by influencing the ECMs secretion and mechanical injury on the glomerular capillaries.
目的研究血小板源生长因子(PDGF)对肾小球系膜细胞(MC)表型转化的影响，并探讨丝裂素活化蛋白激酶(MAPK)信号转导途径在其作用中的调控机制。
Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.
结论护肾固精方治疗系膜增殖性肾炎等肾小球疾病的作用机理之一，可能与抑制MC增殖和促其细胞凋亡有关。
Conclusion One of action mechanism of HSGJF treating mesangial proliferative nephritis and other renal glomerular diseases is to inhibit MC proliferation and promote apoptosis.
结果：肾小球系膜区FN与系膜细胞增生、肾小球损伤程度及肾小管间质损伤程度均呈正相关。
Results Positive correlations were found between the degree of FN in glomerular mesangium or basement membranes and glomerular lesion grading or tubulointerstitial lesion grading.
方法：用图像分析系统测量多柔比星肾病大鼠肾小球面积、系膜区面积和系膜细胞数。
Methods: the glomerular areas, mesangial areas and the number of mesangial cells of Doxorubicin nephropathy in rats were measured by quantitative morphometry study.
其中系膜细胞的收缩在调节肾小球血液动力学如滤过系数和管-球反馈的变化方面可能具有重要的生理意义。
About of which, contraction function may be of physiological significance in modulating glomerular hemodynamics such as filtration coefficient and tubuloglomerular feedback.
首要终点是肾脏活检标本中系膜细胞占肾小球体积的比例变化。
The primary end point was a change in the fraction of glomerular volume occupied by mesangium in kidney-biopsy specimens.
给大鼠注射抗胸腺细胞血清（ATS）复制系膜增生性肾小球肾炎即ATS性肾炎（ATSN）模型。
The model of mesangioproliferative nephritis of rats, namely, anti- thymocyte serum nephritis (ATSN) was established by repeated injection of rabbit antiserum against rat thymocytes.
给大鼠注射抗胸腺细胞血清（ATS）复制系膜增生性肾小球肾炎即ATS性肾炎（ATSN）模型。
The model of mesangioproliferative nephritis of rats, namely, anti- thymocyte serum nephritis (ATSN) was established by repeated injection of rabbit antiserum against rat thymocytes.
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