胃癌中部分患者并不经历肠上皮化生或异型增生阶段。
Some gastric cancer patients did not undergo intestinal metaplasia or gastric mucosa dysplasia.
目的：探讨CDX2和PTEN蛋白表达与胃黏膜肠上皮化生的关系。
Objective: To study the relationship of expression of CDX2 and PTEN proteins and gastric metaplasia .
提示HP感染是肠上皮化生的促进因素之一，继而增加患胃癌的危险性。
It indicated that HP infection may be one of the factors to induce intestinal metaplasia and so to increase the risk of carcinoma of stomach.
作者认为，除注意肠上皮化生和萎缩性胃炎等表现外，各种不典型增生现象也很重要。
Beyond the well known intestinal metaplasia and chronic gastritis, we found also other atypia or dysplasia.
多种因素与胃癌的发生相关，如环境、饮食、幽门螺杆菌感染、慢性萎缩性胃炎和肠上皮化生等。
There are well-known risk factors for gastric cancer such as environment, foods, Helicobacter pylori infection of the stomach, chronic atrophic gastritis and intestinal metaplasia.
结论对胃黏膜异型增生和肠上皮化生等病变患者的胃镜随访有利于提高胃癌(特别是早期胃癌)的检出率。
Conclusion Gastroscopy and follow-up of patients with intestinal metaplasia or gastric mucosa dysplasia help to detect gastric carcinoma, especially early-stage gastric carcinoma.
结果：由慢性浅表性胃炎→胃粘膜肠上皮化生→轻度异型增生→重度异型增生→胃癌，端粒酶阳性率逐渐增高，分别为0 %、42 9%、40 0 %、75 0 %、84 0 %。
Results: The positive rate of telomerase in chronic superficial gastritis, intestinal metaplasia, mild dysplasia, severe dysplasia and gastric cancer was 0%, 42.9%, 40.0% 75.0%, 84.5% respectively.
此外，几项回顾性研究表明食管柱状上皮肠化生能很好的界定腺癌的发病风险，而杯状细胞不能。
In addition, several retrospective and outcome studies suggest a well-defined risk of neoplasia in patients with esophageal columnar metaplasia, but without goblet cells.
此外，几项回顾性研究表明食管柱状上皮肠化生能很好的界定腺癌的发病风险，而杯状细胞不能。
In addition, several retrospective and outcome studies suggest a well-defined risk of neoplasia in patients with esophageal columnar metaplasia, but without goblet cells.
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