结果：单独DEX诱导具有轻微的肝脏毒性。
Results: Single dose of DEX made mild liver toxicity by inducing CYP450.
目的利用毒理基因芯片技术研究四环素肝脏毒性效应的分子机制。
Objective to study the molecular mechanism of the toxic effect for tetracycline acting on liver using toxicological microarray.
黄芪在拮抗砒石致大鼠氧化性损害及其对肝脏毒性可能起到一定程度的作用。
Oral administration of astragalus membranccus and arsenolite together may decrease the oxygen radical damage and the liver injury induced by arsenolite in rats obviously.
目的：利用基因芯片技术研究抗结核病药物利福平对大鼠肝脏毒性效应的分子机制。
Objective: To investigate the gene expression profiles of rat liver tissue injured by rifampicin (RFP) using cDNA microarrays.
因发现肝功能异常，高剂量组提前中止试验，提示CSL - 111潜在的肝脏毒性。
This highest dosage was discontinued early because of indications it caused a certain elevation in liver function tests, suggesting possible harmful liver effects.
这种情况通常出现在某些存在不可预知肝脏毒性的药物中，而且可能导致一些患者出现急性肝衰竭。
It is often associated with a drug of unpredictable liver toxicity, and may be the cause of acute liver failure in some patients.
结论天然雄黄可导致小鼠肝损伤，酸化精制后对肝脏毒性显著降低，雄黄毒性成分可能为可溶性砷盐。
CONCLUSION: Crude realgar could induce significant liver oxidative injury, which could be reduced by purified realgar. Soluble arsenic salt may be major toxic ingredient.
在今后的研究中，如何改善肝脏体外模型的培养条件及完善药物肝脏毒性研究体系是急需解决的课题。
For the future, there is a need for better culture conditions and more complete system of the drug toxicology research.
它使人们采取生活方式方面的预防措施，以保护肝脏免受额外伤害，特别是通过戒酒和停止使用具有肝脏毒性的某些药物。
It allows lifestyle precautions to be undertaken to protect the liver from additional harm, specifically, by eliminating alcohol and certain drugs which are toxic to the liver.
很多文献报道，灰黄霉素治疗脓癣仍是首选药物，但由于该药的肝脏毒性大，因此目前较少应用于儿童脓癣的治疗。
There are many reports that griseofulvin is the first choice for kerion, but it can hardly be used in children for its hepatic toxicity.
结果：不良反应临床表现以肌肉毒性反应常见，其次为肝脏毒性反应以及其它不良反应（神经系统反应、关节肿痛、过敏等）。
RESULTS:ADRs were mostly seen in the toxic reactions of muscle, followed by toxic reactions of liver and other adverse reactions such as nervous system reaction, pain in joints, allergies, etc.
而后者是药品研究人员特别感兴趣的，因为药物毒性往往出现在肝脏。
The latter are of particular interest to pharmaceutical researchers, since drug toxicity often shows up in the liver.
脉心导敏与硝酸甘油不同，在肝脏不能迅速失活，因而可望具有可靠的临床效果，本品毒性小，副作用极为轻微。
Unlike nitroglycerine, it is not rapidly inactivated in the liver and a reliable clinical effect can be expected. Toxicity is low-effects are minimal with Motazomin.
数据也暗示肝脏和肾脏可能是乙苯毒性攻击目标。
Data also suggests that the liver and kidneys may be a target of toxicity for ethylbenzene.
其他还有肝毒性或肝脏损伤以及影响血压和导致出血等警告。
Other warnings include hepatotoxicity or liver damage, effects on blood pressure and bleeding.
甲型肝炎是一种病毒性肝脏疾病，它可造成轻度或严重疾患。
Hepatitis a is a viral liver disease that can cause mild to severe illness.
这些健康风险与毒性影响包括：器官的蜂窝状变异、肝脏中更多急性的衰老迹象、酶功能干扰、繁殖器官异常。
These include cellular changes in organs, more acute signs of ageing in the liver, enzyme function disturbances, and changes in the reproductive organs.
病理基础是预处理毒性引起肝脏内肝小叶3区内的血窦内皮细胞以及肝细胞损害所致。
The basis of pathology of vod is thought resulting from injury of hepatocytes and endodermis cells surrounding the central veins in zone3of the liver acinus by regimen-related toxicity.
转氨酶水平轻微升高可能反映了甲氨蝶呤对肝脏的早期毒性作用，尽管也可能是全身感染引起的非特异性反应。
The slightly elevated levels of aminotransferases may reflect an early toxic effect of methotrexate on the liver, although a nonspecific response to a systemic infection is also possible.
结论双乙烯酮具有明显的肝脏和肺脏毒性。
Conclusion Diketene has obvious toxic effects on liver and lung.
在离体条件下，以鲤鱼肝脏erod酶为生物标志物研究了壬基酚聚氧乙烯醚及壬基酚的毒性效应。
The toxical effects of nonylphenol ethoxylates and nonylphenol were studied with EROD in liver of carp as biomarker under external condition.
重点阐述了镉对肺、骨、肾、心血管、免疫系统、遗传、肝脏、生殖系统的毒害及其毒性作用机制。
The toxicological effects and the toxigenicity mechanism of the cadmium to lung, bone, kidney, blood vessel, immunity system, descendiblity and liver and procreation system were explained.
由于四氯甲烷具有一定的毒性会破坏人体及动物肝脏，并且会破坏臭氧层。
Because the toxicity of tetrachloromethane would destroy certain human and animal liver, and damage the ozone layer.
肝脏是大部分药物转化代谢的场所，一些药物在肝脏代谢时，其本身或其代谢产物可对肝细胞产生直接或间接的毒性损伤。
The liver is the majority of medicines transformation metabolism place, when liver metabolism, some medicines itself and its metabolite may have direct or the indirect toxic damage to the liver cell.
铜中毒是指家畜摄食铜元素过多，或铜在肝脏等组织中大量蓄积，因突然释放进入血液循环所引起的一种重金属中毒性疾病。
Copper poisoning is a kind of metal poisoning disease which caused by animal intake too much copper, or remaining a lot of copper in the liver and quickly into blood circulation.
现在肝脏血液中的脂肪酸水平明显增高导致了肝细胞毒性。
Now the liver is flooded with fatty acids that promote hepatocellular lipotoxicity.
现在肝脏血液中的脂肪酸水平明显增高导致了肝细胞毒性。
Now the liver is flooded with fatty acids that promote hepatocellular lipotoxicity.
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