羟基积雪草苷在大鼠肝微粒体中的代谢稳定性很高。
The metabolic stability of madecassoside in liver microsomes is good.
结论石榴皮对大鼠肝微粒体脂质过氧化具有保护作用。
CONCLUSION Punica granatum L. has protective effect against rat liver microsomal lipid peroxidation.
目的：建立一种结合肝微粒体代谢的抗疟药体外筛选方法。
AIM: To develop an in vitro assay incorporated with metabolism for screening antimalarials.
用大鼠肝微粒体体外代谢法对HH07A进行了代谢转化研究。
The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes.
方法采用大鼠肝微粒体体外温孵法，研究对蓝萼甲素的代谢转化。
METHODS The metabolic transformation of glaucocalyxin A was studied by using rat liver microsomal incubation containing the NADPH-generating system in vitro and in rat bile.
目的研究石榴皮提取物对大鼠肝微粒体脂质过氧化损伤的保护作用。
OBJECTIVE To investigate the protective effect of Punica granatum L. on rat liver microsomal lipid peroxidation.
结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
目的建立以硝苯地平为探针药物测定大鼠和犬肝微粒体活性的HPLC/MS。
OBJECTIVE To establish a HPLC/MS method to determine microsomes activity in vitro using nifedipine as a probe drug.
结果提示镉、铅、汞可能通过降低微粒体酶的新生合成，抑制肝微粒体药物代谢酶。
The results suggested that the inhibition of hepatic microsomal drug-metabolizing enzymes by cadmium, lead or mercury was produced by decreased neosynthesis of microsomal enzymes.
目的研究吴茱萸次碱(WZY)在人肝微粒体中对细胞色素P 450酶的抑制作用。
OBJECTIVE to determine the inhibitory effect of rutaecarpine (WZY) on cytochrome P450s in human liver microsome.
PH引起的氧化应激和炎症因子不仅阻碍肝细胞增殖，还可损伤肝微粒体CYP450酶。
Oxidative stress after PH can not only impede hepatocellular proliferation, but also damage liver microsomal CYP450.
同时肝微粒体蛋白含量、CYP450含量和红霉素-N-脱甲基酶活性呈现有一定的性别差异。
And the liver microsome protein content, CYP450 content and erythromycin-N-demethylase activity appear some gender differences.
文章报告了阳离子表面活性剂十二烷基硫酸钠(SDS)对大鼠肝微粒体脂质过氧化模型的影响。
The effects of sodium dodecyl sulfonate (SDS) on lipid peroxidation in rat liver microsomal system has been studied.
这些结果表明，CBD对鼠类巨噬细胞具有毒性作用，并且可能受肝微粒体混合功能氧化酶的影响。
The results indicate that CBD exerts toxic effect on the macrophages of rat and mouse and the toxicity may be altered by liver microsomal MFO.
氧化苦参碱是自中药苦参中提取的一种生物碱，本文就其对小鼠肝微粒体药物代谢酶的影响进行了探讨。
The effect of Oxymatrine(OMT), isolated from Sophora flavescens Ait, on the hepatic microsomal drug-metabolism enzyme have been investigated.
目的：研究反式白藜芦醇及反式白藜芦醇苷对大鼠肝质量、肝微粒体蛋白质及细胞色素P 450的影响。
Objective: to study the effects of trans-resveratrol and trans-piceid on liver weight, contents of microsomal protein and cytochrome P450.
目的探讨丙烯腈(acn)对睾丸精原细胞dna的损伤作用及经肝微粒体酶活化前后该损伤程度的差异。
Objective to explore acrylonitrile (ACN) induced DNA damage on Newt spermatogonia, and to compare the difference in DNA damages before and after microsomal enzyme activation.
试验结果表明，大、中剂量的预知灵和人参煎液均能显著降低肝微粒体LPO水平并提高其SOD的活力。
The results showed that high and middle dose of Yuzhiling could apparently reduce the level of LPO and increase the activity of SOD in the hepatic microsome, which Rensheng decoction could do.
报道了用GC／MS方法及衍生化技术研究6甲氧基正丁苯酞（MBP）在大鼠肝微粒体中的代谢转化结果。
The in vitro biotransformation of 6 methoxy butyl phthalide (MBP) by phenobarbital induced rat liver microsomes was investigated by GC/MS and GC/MS with TMS derivatization.
乙醇是最常见的病因，作为肝毒素能阻碍肝细胞内的线粒体和微粒体的功能，导致脂质沉集。
Alcohol, the most common cause, is a hepatotoxin that interferes with mitochondrial and microsomal function in hepatocytes, leading to an accumulation of lipid.
乙醇是最常见的病因，作为肝毒素能阻碍肝细胞内的线粒体和微粒体的功能，导致脂质沉集。
Alcohol, the most common cause, is a hepatotoxin that interferes with mitochondrial and microsomal function in hepatocytes, leading to an accumulation of lipid.
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