• 右美沙芬的代谢表型研究为中国本地人的异丁喹4-羟化酶(CYP2D6)多态性提供了新的信息。

    Dextromethorphan metabolic phenotyping provides a new information for debrisoquine 4-hydroxylase (CYP2D6) polymorphism in native Chinese.

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  • 苯胺羟化酶在第9周也有升高。

    Aniline hydroxylase was also high in the 9th week.

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  • 介绍了近年来苯直接羟化合成苯酚的研究进展和合成方法。

    Recent progress and synthesis methods on direct hydroxylation of benzene to phenol are systematically introduced.

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  • 目的为了诊断和治疗21羟化酶缺乏导致的女性假两性畸形。

    Objective To diagnose and treat female pseudohermaphroditism caused by 21 - hydroxylase deficiencies.

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  • 根据苯酚羟化酶基因高度保守序列设计一对该基因的特异引物。

    A pair of specific primers of gene encoding phenol hydroxylase was designed by oligonucleotide high conservative sequence.

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  • 目的观察中国人CYP2C19基因型与奥美拉唑羟化代谢的关系。

    AIM to study the relation of CYP2C19 genotype to omeprazole metabolism in Chinese healthy subjects.

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  • 目的:探讨药物依赖行为和酪氨酸羟化酶在成瘾过程中的相互关系。

    AIM: To observe the relationship between the drug dependence behavior and levels of tyrosine hydroxylase (th) in drug acquisition process.

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  • 苯酚直接羟化制备苯二酚为液固相的强放热快反应,催化剂的活性衰减很快。

    The hydroxylation of phenol to produce dihydric phenol is a rapid and strongly exothermal reaction, the activity of the complex-oxide catalyst decreased rapidly.

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  • 中文摘要:目的:建立清醒自由活动大鼠脑内酪氨酸羟化酶活性的测定方法。

    Objective: To set the measuring method of tyrosine hydroxylase activity in the brain of conscious rats.

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  • 目的对中国人非经典型21羟化酶缺乏症(21OHD)基因型进行研究。

    Objective To investigate the genotype in Chinese patients with nonclassical 21 hydroxylase deficiency (NC 21OHD).

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  • 通过比较认为,氧化还原法是未来实现苯直接羟化合成苯酚工业化的优选方法。

    And it is considered that the reduction-oxidation method would be the optimum method for realizing in industry direct hydroxylation of benzene to phenol.

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  • 在小鼠和烟草中,这是通过过渡表达聚羟化酶来实现的,类似于酵母和昆虫细胞培养。

    In mice and tobacco, this was overcome by over-expression of prolyl hydroxylase, analogous to what has been done in yeast and insect cell culture.

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  • 水杨酸羟化酶是细菌萘降解途径中的关键酶,它能催化水杨酸脱羟和羟化,生成儿茶酚。

    The salicylate hydroxylase, a important enzyme in bacterial naphthalene degradation pathway, catalyzes the decarboxylative hydroxylation of salicylate to form catechol.

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  • 羊水细胞DNA分析是先天性肾上腺皮质增生症21-羟化酶缺陷的产前诊断的可靠方法。

    DNA analysis of amniocytes was a feasible method for the prenatal diagnosis of congenital adrenal hyperplasia with 21-hydroxylase deficiency.

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  • 通过与已报道环氧木脂素类化合物碳谱数值比较,得到了木脂素羟化和苷化位移效应规律。

    The rule of hydroxylation and glycosidation shift effects on bisepoxy lignans were obtained by comparing the information of 13C NMR with known analogous.

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  • 系统阐述了羟化反应机理,并指出加氧酶活性中心少数氨基酸残基是影响羟化反应的关键因素。

    Some amino acid residues in the active center of mono-oxygenases were pointed out to be the main factors to the hydroxylation.

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  • 结论羊水细胞DNA分析是先天性肾上腺皮质增生症2 1羟化酶缺陷的产前诊断的可靠方法。

    Conclusion DNA analysis of amniocytes was a feasible method for the prenatal diagnosis of congenital adrenal hyperplasia with 21-hydroxylase deficiency.

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  • 在实验中我们观察到苯酚羟化反应中不仅有苯醌生成 ,而且生成的苯醌还能促进羟化反应 。

    The charge transfer interactions of dobutamine with p benzoquinone and chloranil were investigated in ethanol medium, the reactions of Dobutamine with p benzoquinone and chloranil are complete.

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  • 目的:观察脑缺血后抑郁模型大鼠下丘脑酪胺酸羟化酶(TH)表达及益肾调气方药的干预作用。

    Objective:To observe the expression of Tyrosine Hydroxylase(TH) of Hypothalamus in post-stroke depression rat model and effects of Yishen Tiaoqi decoction.

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  • 这是首次用热不对称交错pcr法从木本植物的基因组dna克隆到类黄酮3'-羟化酶基因。

    This was the first time to clone flavonoid 3 '-hydroxy-lase gene from genomic DNA of woody plants by thermal asymmetric interlaced PCR.

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  • 本发明涉及一种用于制备链烯基化的羟化芳族化合物、苯并二氢吡喃化合物和其酰化衍生物的方法。

    The present invention relates to a process for the manufacture of alkenylated hydroxylated aromatic compounds, of chroman compounds and of their acylated derivatives.

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  • 目的分析19例21羟化酶缺陷症(21OHD)患者的临床和随访资料,提高该病的诊断和治疗水平。

    Objective Clinical data of 19 Chinese patients with 21 hydroxylase deficiency (21OHD) were analyzed to improve the diagnosis and treatment level.

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  • 槲皮素竞争性抑制CYP3A2右美沙芬N脱甲基反应,非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

    QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction.

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  • 介绍了锰及锰卟啉对超氧化物、羟化自由基、脂质过氧化等自由基的抑制作用,并初步讨论了它们的作用机理。

    This paper mainly introduces the inhibition function of manganese and manganese porphyrins to superoxide and hydroxyl radicals, lipid peroxidation.

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  • 目的探讨中国汉族人色氨酸羟化酶(TPH)基因A 218c多态性与单相抑郁症及其症状表型的遗传关联性。

    Objective to investigate the association among tryptophan hydroxylase (TPH) gene A218C polymorphism, unipolar depression (UPD) and symptom phenotypes in han nationality of Chinese.

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  • 研究小组发现血清VDR的基因型并不影响血清25-羟化维生素D25-hydroxyvitaminD水平。

    The team found no differences in serum 25-hydroxyvitamin D by VDR genotype.

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  • 结论:NURR1基因结合神经干细胞有效改善了帕金森病模型症状,提高移植后酪氨酸羟化酶阳性神经元细胞的数量。

    CONCLUSION: NURR1 gene combined with NSC can effectively ameliorate PD models symptoms and elevate the number of tyrosine hydroxylase positive neurons after transplantation.

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  • 其位移效应规律对于双环氧四氢呋喃木脂素的结构确定,尤其糖的连接位置和羟化位置的指定,提供了一定的判断依据。

    The rules of displacement provided suggestion for the confirmation of double-tetrahydrofuran lignans, especially the position of hydroxylation and glycosylation.

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  • 增加EGR1表达可以激活其他信号分子的转录,包括CDK5和酪氨酸羟化酶,对神经细胞生长和分化有长期影响(2,3)。

    Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).

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  • 增加EGR1表达可以激活其他信号分子的转录,包括CDK5和酪氨酸羟化酶,对神经细胞生长和分化有长期影响(2,3)。

    Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).

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