除了MHC外,6号染色体上的该区域也包含一组组蛋白基因。
In addition to the MHC, this region on chromosome 6 also contains a cluster of histone genes.
精神分裂症的分子遗传学院会(MGS)精确确定了精神分裂症和6号染色体区域上的基因间的联系,它介导基因表达,比如组蛋白。
The Molecular Genetics of schizophrenia (MGS) consortium pinpointed an association between schizophrenia and genes in the chromosome-6 region that mediate gene expression, such as histones.
下面的视频是关于在癌症细胞里的常规基因表达是如何进行组蛋白乙酰化作用(acetylationofhistone)的。
Here's a video that animates the acetylation of histone proteins in the regulation of gene expression in cancer cells.
高脂肪组产的子鼠的葡萄糖代谢基因有些表观改变,组蛋白乙酰化环节——能打开DNA环使基因转录更容易——是其中一处改变。
The high-fat offspring also had epigenetic modifications to genes that regulate glucose metabolism.
所以当他们成形的时候,组蛋白被脱离并且被一种叫做鱼精蛋白的分子代替。它可以把DNA组装成更加紧密的一束,这些基因是无法被阅读的。
So when they form, the histones are stripped off and replaced with another molecule called protamine, which shapes the DNA into an even tighter bundle, where the genes cannot be read.
组蛋白还起到了基因开关的作用,因此它们编码的信息可以被复制并且传递到细胞的其它部位。
Histones also play a role in turning genes on so that their coded instructions can be copied and sent to other parts of the cell.
配型涉及10组蛋白,或者标志基因;越多标志基因可以成列,则表示配型越是接近。
There are 10 different proteins, or markers, involved; the more markers that line up, the closer the match.
DNA周围的学习和记忆基因束靠近乙酰基群,注入一种能促进乙酰基群变成任何一种组蛋白分子的酶。
The cluster of learning and memory genes on the surrounding DNA ends up close to the acetyl group.
组蛋白是涉及到调控基因的蛋白质。
Histones are proteins involved in regulating genes being turned on and off.
组蛋白既保护DNA也在它们与DNA结合形成染色质时调节基因表达。
Histone proteins both protect DNA and regulate genes as they combine with DNA to form chromatin.
当甲基加到组蛋白后,这些基团会修饰它的性质并改变它上面特定基因的表达频率。
When methyl groups are added to a histone, they modify its properties and alter the frequency at which a particular gene is expressed.
相反,表观遗传过程主要是将化学结合到基团或组蛋白,后者是与DNA交织在一起形成染色体,从而激活或关闭基因。
Instead, epigenetic processes attach chemical groups to genes or to histones, proteins that are intertwined with DNA to form chromosomes, to activate genes or to shut them down.
我们的数据提供了一个在基因组功能中组蛋白甲基化和染色质组织的新观点。
Our data provide new insights into the function of histone methylation and chromatin organization in genome function.
DNA的低甲基化可能在异常组蛋白修饰的协同下引起某些T细胞基因的异常活化,导致狼疮自身免疫的发生。
DNA hypomethylation, likely to be cooperating with aberrant histone modification, may induce the activation of some t cell genes and development of autoimmunity in SLE.
新方法现在允许某些时候研究人员直接显示那些基因由于组蛋白而被激活或失活。
New methods now allow researchers to sometimes directly show which genes have been activated or deactivated by the histones.
一组称为多梳抑制复合物1(PRC1)蛋白质沉默基因必须先结合到特定的组蛋白上的甲基化位点。
A group of proteins called the polycomb repressive complex 1 (PRC1) that silences genes must first bind to a particular methylated address on a histone and.
组蛋白是染色质的核心,其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
在染色体中,SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
这种疫苗被称作“重组蛋白疫苗”,它采用了一种流感病毒蛋白质,这种蛋白质是通过改变一种感染昆虫细胞的病毒的基因而合成的。
It's called a recombinant protein vaccine and USES an influenza virus protein that's made by genetically altering a virus that infects insect cells.
其他的工作集中在组蛋白乙酰化,这种化学修饰可以使DNA从组蛋白缠绕中解离出来,产生基因活性。
Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.
组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关;
The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.
组蛋白尾端不同的化学修饰往往和基因的表达调控有着密切的关系,乙酰化就是常见的一种修饰形式。
Gene expression is often closely related to the different chemical modification ends of protein, acetylation is a kind of common form of modification.
乙酰化反应使组蛋白让DNA解螺旋,允许了基因的表达发生,因此抑制乙酰化反应将从总体上降低基因的表达。
Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
结合以上去乙酞化酶抑制剂的实验结果,我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。
Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.
目的观察dna甲基化和组蛋白乙酰化对人结肠癌细胞系癌相关基因的表达和细胞周期的影响。
Purpose to investigate the effects of DNA methylation and histone acetylation on the expression of tumor associated genes and cell cycle progression in human colonic cancer cells.
本试验以EMA - 1基因重组蛋白为诊断抗原,用EL IS A方法对延边地区马巴贝斯虫病进行了血清学调查。
Babesiosis equi serum epidemiology investigations in yanbian area were using the EMA-1 genetic recombinant protein as diagnosis antigen by the ELISA.
组蛋白是植物基因组的重要组成部分。
组蛋白乙酰化和去乙酰化可调节染色体的多种功能,例如基因表达和染色体分离等。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能,例如基因表达和染色体分离等。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
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