本文综述了近年来所纯化的主要的糖基化转移酶和去糖基化酶的性质和应用。
The main characteristics and applications of these enzymes purified in recent years were reviewed.
这些数据表明晶状体蛋白的非酶糖基化可能会导致白内障。
These data suggest that nonenzymatic glycosylation of lens crystallins may contribute to cataract formation.
当血糖过多时，可以使上述酶的酶蛋白糖基化，催化活性降低，过暇化氢和氧自由基清除减慢。
When hyperglycaemia, may cause the above enzyme the zymoprotein glycosylation, the catalytic activity to reduce, crosses the free time hydrogen and the oxygen free radical elimination reduces speed.
目的以非酶糖基化和自由基学说探讨心肌老化的发生机制。
Objective To investigate the mechanisms of nonenzymatic glycosylation inducing myocardial aging and free radical theory.
目的：研究某些中药有效成分对非酶糖基化的抑制作用。
Objective: to investigate the inhibitory effects of some Chinese herb components on the nonenzymatic glycosylation.
目的研究牛磺酸对糖尿病大鼠肾脏氧化应激反应和非酶糖基化的抑制效果。
Objective to investigate the inhibitory effects of taurine on oxidative stress and nonenzymatic glycation in kidney of diabetic rats.
结论减轻肾脏自由基代谢紊乱和抑制非酶促糖基化可能是济肾汤改善糖尿病大鼠肾脏病变的重要机制。
Conclusion Attenuation of free radical metabolism disturbance and inhibition of non enzymatic glycosylation in kidney may be an important mechanism of JST to ameliorate renal lesions in diabetic rats.
酪氨酸酶翻译后加工和糖基化。
Posttranslational processing and glycosylation of tyrosinase.
品状体结构蛋白的非酶糖基化引起晶状体构象变化在糖尿病性白内障的发生中起重要作用。
It is vital in the diabetic cataract formation that the non-enzymic glycosylation of the lens structural proteins by glucosamine induces conformational changes in the lens.
结论：GSPE能够抑制STZ糖尿病大鼠非酶糖基化反应，对其心脏超微结构有一定保护作用。
Conclusion: GSPE can inhibit nonenzymatic reactions of glycosylation in STZ-induced diabetic rats and protect the myocardial ultra-structure.
它是通过糖基转移酶催化完成的，其中糖核苷酸是糖基化过程中糖的供体。
Sugar nucleotides are sugar donors to aglycone in glycosylation, which is catalyzed by glycosyltransferases.
在糖基化工程中，通过酶法对蛋白质进行糖基化修饰和对天然糖蛋白去糖基化是研究糖蛋白结构与功能的重要手段。
In glycosylation engineering, glycoproteins are modified by glycosylation and deglycosylation. Glycosyltransferases and the enzymes of deglycosylation play important roles in the processes.
糖基转移酶（GT）催化许多生物大分子的糖基化反应。
Glycosyltransferases (GTs) catalyze the reaction of glycosylation of various cellular macromolecules.
糖基化和其他非酶翻译后修饰的蛋白质有牵连在糖尿病并发症和其他条件。
Glycation and other non-enzymic post-translational modifications of proteins have been implicated in the complications of diabetes and other conditions.
ADP核糖基化因子(ARF)在膜泡运输中具有重要作用，其活性受gtp酶活化蛋白(gap)的调控。
ADP ribosylation factors (ARFs) are critical in the vesicular trafficking pathway. ARF activity is controlled by GTPase-activating proteins (GAPs).
试验以抑制非酶糖基化反应活性为指标，通过单因素试验筛选了适宜碳源、氮源、无机盐以及复合营养因子，通过正交试验进一步优化培养基组成。
Effects of carbon sources, nitrogen sources and growth factors on the bioactivity inhibition of non-enzymatic glycation reaction of biotransformation products of Ginkgo biloba L.
试验以抑制非酶糖基化反应活性为指标，通过单因素试验筛选了适宜碳源、氮源、无机盐以及复合营养因子，通过正交试验进一步优化培养基组成。
Effects of carbon sources, nitrogen sources and growth factors on the bioactivity inhibition of non-enzymatic glycation reaction of biotransformation products of Ginkgo biloba L.
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