这是因为对最佳，也是最后一类有效抗疟药——青蒿素，产生耐药性所导致的失败。
This failure is due to resistance to artemisinin, our best and last class of effective antimalarials.
另外，专家称，如果市场上只有青蒿素类的药品，一段时间以后最终还是会导致抗药性的出现。
What's more, public health experts say that the artemisinin-only pills on the market will inevitably engender drug resistance over time.
问：为何您在青蒿素耐药性并未引起关注的时候就研究青蒿素类复方药呢？
Q: Why did you research ACT for malaria at a time when there were no concerns about resistance to artemisinin?
结果1990年至1999年细菌L型常见菌株耐药性逐年上升，特别是青霉素类大部耐药；
Results From 1990 to 1999, the drug resistance to common L-form bacteria was rising year after year, especially to penicillins.
皮肤细菌感染的不断增加对抗生素类药会产生抗药性。
An increasing number of bacterial skin infections are resistant to antibiotic medicines.
目前，疟原虫除了对青蒿素类未产生明显耐药性外，几乎对所有常规抗疟药都产生了抗性，然而新抗疟药的研制需要足够长的时间周期。
With the exception of artemisinin derivatives to which it has not yet developed marked resistance, Plasmodium has now developed resistance to almost all of the conventional anti-malarial drugs.
目的了解城区蚊虫抗药性情况，科学指导蚊类控制。
Objective To know the resistance of flies and mosquitoes in Luoyang City, scientific guidance to control them in the city.
结论铜绿假单胞菌的耐药性日趋严重，两类拓扑异构酶基因突变和泵出机制形成了铜绿假单胞菌对喹诺铜类药物耐药的主要机制。
The resistance to quinolones in clinical isolates of Pseudomonas aeruginosa is due to the mutations of two types of topoisomerase plus efflux pump.
目的观察吉西他滨联合卡培他滨治疗蒽环类耐药性晚期乳腺癌的疗效与毒性反应。
Objective To observe the results of gemcitabine combined with capecitabine on anthracycline-resistant breast cancer.
在有些国家，在治疗开始前便进行耐药性测试，以便确定HIV病毒是否已经对某一类药物具有了耐药性。
In some countries a drug resistance test can be carried out before treatment is started in order to determine whether the HIV is already resistant to any of the drug classes.
因此，我国灰葡萄孢抗腐霉利等二甲酰亚胺类杀菌剂的分子机制尚不清楚，其高渗敏感性和抗药性可能另有原因。
Therefore, the molecular mechanism of the sensitivity to high osmotic stress and the resistance to dicarboximide fungicides such as procymidone needs a further study in these strains.
以方剂药性特征为基础探讨消渴方的药性特征和寒凉类、温热类方剂的药性特征。
The formulas with cool or warm nature and the formula used to treat wasting-thirst were studied based on the concept of formula nature.
他说，这种细菌已经具有把消毒剂和抗生素从它们的细胞中提取出来的功能，也就是说它们的DNA突变使得它们对ciprofloxacin环丙沙星一类的抗生素有了耐药性。
He said that the bacteria had adapted to pump out both the disinfectant and antibiotic from their cells, as well as showing a DNA mutation that made them resistant to ciprofloxacin-type antibiotics.
结果通过聚类分析，将河北省德国小蠊的抗药性水平分为4类。
Results According to the theory of cluster analysis processing, the data of resistance levels were clustered to four categories to 4 groups.
结论大量而持续地使用杀虫剂可产生抗药性，因此要加强对蚤类抗药性监测，轮换使用灭蚤药物，科学、合理用药。
Therefore, the resistance of insecticide must be monitored constantly when killing fleas. The insecticide must be used scientifically and rationally.
ESBL阳性与ESBL阴性大肠埃希菌相比较其对，喹诺酮类、氨基糖甙类、磺胺类的耐药性差异存在显著性（P<0.05）；
Between the positive strains for ESBL and the negative strains , there were some significant antimicrobial resistance differences(P<0.05);
ESBL阳性与ESBL阴性大肠埃希菌相比较其对，喹诺酮类、氨基糖甙类、磺胺类的耐药性差异存在显著性（P<0.05）；
Between the positive strains for ESBL and the negative strains , there were some significant antimicrobial resistance differences(P<0.05);
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