QTL等位基因变异与孟德尔基因变异具有类似的分子基础,即基因表达或蛋白质功能发生改变。
The allelic variations at QTL has similar molecular basis to the variations at simple Mendelian loci and the basis is that gene expressions or protein functions vary.
主要结果如下:1、对24个玉米自交系进行了SSR分析,44对引物共检测出136个等位基因变异,每对引物检测出2 - 7个等位基因,平均为3.09个。
The main results are as following: 1. By analysing 24 maize inbred lines with SSR, 136 alleles was detected from 44 pairs of primers, 2-7 alleles of each pair, average was3.09.
研究人员寻找不存在与父母中的杂合变异体,而不是寻找每位亲本携带一个等位基因的纯合变异体。
Instead of looking for homozygous variants where each parent carried an allele, the researchers were looking for heterozygous variants that were also not present in the parents.
研究报告写道:“在87名抑郁症病人中有9名受试者被发现些带有变异的等位基因。
The paper reporting the study states: "Nine subjects from a cohort of 87 depression patients were found to carry the mutant allele.
研究人员注意到CRP基因变异体影响了血浆CRP水平,提出与高水平CRP有关的CRP等位基因将导致心脏病发生的危险增加。
Noting that CRP gene variants affect plasma levels of CRP, the researchers suggest that CRP alleles associated with higher CRP levels would confer an increased risk of heart disease.
另一方面,无论体力活动水平如何,CETP变异微小等位基因携带状态与心肌梗死的风险减少相关。
On the other hand, minor-allele carrier status of the CETP variant was associated with a reduced risk of mi regardless of activity levels.
然而,这一研究发现符合过去的研究结果,那就是在居无定所不断迁徙的人口中7R和一套统称为“长等位基因”的DRD4的类似变异体更加相同。
Nevertheless, this discovery fits past findings that 7R and a set of similar variants of DRD4, known collectively as "long alleles", are more common in migratory populations.
发生糖尿病之前的变异寻找每一个等位基因会提高10%-25%的患病风险。
The pro-diabetic variations that were found tended to increase the risk of the disease by between 10% and 25% per allele.
发生糖尿病之前的变异寻找每一个等位基因会提高10%-25%的患病风险。
The pro-diabetic variations that were found tended to increase the risk of the disease by between 10% and 25% per allele.
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