目的研究未折叠蛋白反应(upr)在神经分化过程中的作用。
Objective To explore the function of unfolded protein response (UPR) in the differentiation of neural cells.
神经干细胞（NSCs）具有高效能的自我更新和神经分化能力。
Neural stem cells (NSCs) possess high potencies of self-renewal and neuronal differentiation.
这一发现为了解神经分化的机制提供了线索，并且为脑病的模拟研究和治疗提供了新途径。
The discovery of intrinsic corticogenesis sheds new light on the mechanisms of neuronal specification, and opens new avenues for the modelling and treatment of brain diseases.
神经分化形态表现为瘤细胞胞质和胞质突起内可见散在或簇状分布的致密核心颗粒，并形成突触样结构。
The ultrastructural features of neural differentiation included scattered or cluster distribution of dense core granules in cytoplasm and cytoplasmic processes;
他将他培养得到的干细胞注入鼠脑，并发现这些干细胞成功地分化成神经系统的各种细胞。
He injected stem cells he had cultured from his patients into mouse brains and found that they successfully differentiated into the various cell types found in the nervous system.
问题关键在于找到正确的诱导干细胞分化成心脏细胞，神经细胞，制造胰岛素的细胞或者其他细胞的生长因子的正确方法。
The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.
利用血液去培育干细胞获得成功以后，朱敏设法诱导它们分化成三种细胞系：先是骨骼和软骨细胞，然后是肌细胞，再是神经元。
Using blood to nourish and grow the stem cells, Zhu managed to induce them to differentiate into three lineages: first bone and cartilage, then muscle, and then neuron.
用一个动物模型，研究者发现：与正常出生体重的新生儿对比，低出生体重儿的神经干细胞更少分支和分化。
Using an animal model, the researchers found less division and differentiation of the neural stem cells of a newborn with low birth weight as compared to normal birth weight.
增加EGR1表达可以激活其他信号分子的转录，包括CDK5和酪氨酸羟化酶，对神经细胞生长和分化有长期影响(2,3)。
Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).
STEM 123检测在移植入小鼠脑中后从人神经干细胞分化的人GFAP +星形胶质细胞。
STEM123 detects human GFAP + astrocytes differentiated from human neural stem cells after transplantation into a mouse brain.
我们推测胚胎基质的某种缺陷不仅损害了神经嵴细胞的移行，也影响ICC的分化和成熟。
It is suspected that the defect of embryo matrix inhibits either the migration of neural crest cell or the differentiation and maturation of ICC.
STEM 123在体外检测从人神经干细胞分化的人GFAP +星形胶质细胞。
STEM123 detects human GFAP + astrocytes differentiated from human neural stem cells in vitro.
STEM 121检测移植的人神经干细胞在小鼠脑的海马中的迁移和分化。
STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.
此外，尚有安全性方面的顾虑，因为有迹象表明从人干细胞分化来的多巴胺神经元可能引发肿瘤生长。
There have also been safety concerns, with signs that dopamine neurons developed from human stem cells can trigger the growth of tumors.
目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
方法采用细胞培养技术、免疫细胞化学方法观察新生大鼠皮层神经干细胞向胆碱能神经元定向分化的时空变化。
Observation the space-time change of cortex nerve stem cell in newborn rat orientation differentiation to cholinergic neuron by cell cultured and immunocyte chemistry methods.
神经突的形成过程被称为神经突生成，是神经元(中枢神经系统的主要细胞成分)细胞分化的第一步。
The formation of neurites, a process called neuritogenesis, is the first step in the differentiation of neurons, the basic information cells of the central nervous system.
CNTF和LIF等在神经干细胞的分化中也有重要作用。
CNTF and LIF are critical for differentiation of neural stem cells.
目的研究丙烯腈（ACN）对体外培养的大鼠胚胎脊髓神经细胞增殖分化的影响。
Objective To explore the effects of acrylonitrile (ACN) on proliferation and differentiation of spinal cord nerve cells of rat embryo in vitro.
目的探讨新生小牛血清对人胎脑海马组织神经干细胞分化的影响。
Objective To investigate the effects of neonatal calf serum on the differentiation of human neural stem cells in the hippocampus.
以免疫荧光法测定分化细胞神经特异性烯醇化酶（NSE）、星形胶质细胞特异性标志（GFAP）的表达。
The expression of NSE and GFAP in the differentiated cells was detected by immunofluorescence.
脂肪来源的干细胞向神经细胞分化应用于中枢神经损伤功能改变有一定的效果，是值得深入研究的课题之一。
The differentiation from the adipose tissue-derived stem cells to neural cells has shown reasonable effect in the functional recovery after central nervous injury, so that it is a worthwhile topic.
实验通过原位分子杂交技术，检测人骨髓巨核细胞分化发育过程中神经生长因子（ NGF）基因表达情况。
The expression of nerve growth factor (NGF) gene during development of megalocaryocytes was studied by in situ hybridization.
标记显示梭形细胞型鳞状细胞癌缺乏神经内分泌分化。
Immunohistochemically, the spindle squamous cell carcinoma was lack of differentiation of the neuroendocrine carcinoma.
神经干细胞的分化更多地决定于培养条件。
The differentiation is dependent largely on the culture conditions.
结论：类缺血处理后的皮质神经元对外源性神经干细胞的分化有促进作用，并能促进其向神经元分化。
CONCLUSION: Cortical neuronal cells injured in ischemia like conditions can significantly promote the differentiation of exogenous NSCs and make them differentiated into neurons more.
目的研究神经干细胞向胆碱能神经元定向分化后对脊髓横断损伤的修复作用。
Objective To observe the effects of transplanting cholinergic neurons after inducing neural stem cells on treating spinal cord injury.
目的：研究视神经损伤后神经胶质细胞去分化的程度及相关分子的表达。
Objective: To investigate the dedifferentiation of glia cells and the expression of related molecules after optic nerve injury.
目的：研究视神经损伤后神经胶质细胞去分化的程度及相关分子的表达。
Objective: To investigate the dedifferentiation of glia cells and the expression of related molecules after optic nerve injury.
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