本综述将着重讨论破骨细胞的生理。
This review will focus on the physiology of the osteoclast .
统计学分析评价其抑制破骨细胞分化效果。
Its differentiation effect on inhibiting osteoclast was assessed with statistics analysis.
另一类细胞叫破骨细胞，在确定不需要的地方可以破坏它。
Another set of cells, osteoclasts, destroy it where it is deemed no longer necessary.
抑制破骨细胞的分化成熟就能有效控制骨的吸收。
The inhibition of the differentiation and maturity of osteoclast will inhibit bone resorption.
TRAP染色显示实验组破骨细胞明显较对照组活跃。
TRAP staining showed osteoclasts in the new bone of the experimental group were more activated than that of the control.
结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration.
目的：探讨伴破骨细胞样巨细胞乳腺癌的临床病理特点。
Purpose To study the clinicopathological features of mammary carcinoma with osteoclast-like giant cells.
另外，RUNX2与破骨细胞和细胞外基质的形成也有关。
RUNX2 is also associated with the formation of osteoclasts and extracellular matrix.
而且可以抑制破骨细胞凋亡，因而可用于治疗骨骼石化症。
目的研究不同诱导因子对大鼠破骨细胞样细胞体外形成的影响。
Objective To investigate the effect of different osteotropic hormones on the formation of rat osteoclast like cell in vitro.
目的：研究阿仑膦酸盐通过凋亡抑制破骨细胞性骨吸收的作用。
Objective: to study the inhibiting effect of alendronate on the apoptosis of osteoclasts.
运动改善骨代谢，增强成骨细胞的活动，抑制破骨细胞的活动。
Sports can improve the bone metabolism, strengthen the movement of OB and control the movement of OC.
目的：探讨可行的获取人破骨细胞样细胞以供进一步研究的方法。
Object: the study is to find a feasibility method of obtaining human osteoclast-like cells for the purpose of further research.
其中单核破骨细胞在第3天、多核破骨细胞在第5天时达到峰值。
Mononucleated osteoclast reached peak level at 3 days after tooth movement, while multinucleated cells reached peak level at 5 days.
破骨细胞细胞核核大，4 ~6个，胞浆伸出丝状或片状伪足。
Osteoclasts had 4 to 6 big nuclei, and cytoplasm extended pseudopodia of filament or sheet shape.
在此论文中阐述了这些因子对破骨细胞的分化和功能具有重要作用。
Here we show that these three factors have critical roles in osteoclast differentiation and function.
而惰性骨钙蛋白的积累反过来会推动破骨细胞发生作用，使他们逐渐的消解骨骼。
Accumulation of inactive osteocalcin instead nudges osteoclasts into action, causing them to gobble up bone.
成骨细胞与破骨细胞间的活动及其相互作用共同影响着骨改建的过程。
The activity between the osteoblast and the osteoclast, with their mutual effects, influence the procedure of bone remodeling.
目的探讨伴破骨细胞样巨细胞肾肿瘤(RT OGC)的临床病理特点。
Purpose To study the clinicopathological features of renal tumors with osteoclast-like giant cells (RT-OGC).
血清TRACP水平与破骨细胞的组织学参数有更强烈的相关性超过腐蚀。
Serum TRACP levels correlated more strongly with histological parameters of osteoclasts than those of erosion.
石骨症的特征是破骨细胞功能出现障碍，使骨吸收减慢，导致骨再建缺陷。
Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.
结论人滞留乳牙牙根吸收面存在大量的破骨细胞，是研究人破骨细胞的一个来源。
Conclusion on the resorbing surface of human deciduous teeth there are large amount of osteoclasts which can be used as a source of studying human osteoclast.
我们得出下列结论：脂联素可能通过影响基质细胞刺激成骨细胞，抑制破骨细胞。
We conclude that adiponectin stimulates osteoblast growth but inhibits osteoclastogenesis , probably via an effect on stromal cells.
在吸收阶段，原来的骨骼组织被破坏而且被叫做‘破骨细胞’的特殊细胞所消除。
During resorption, old bone tissue is broken down and removed by special cells called osteoclasts.
结论：尼尔雌醇可以抑制IL6基因表达，从而抑制破骨细胞骨吸收，减少骨量丢失。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
减少破骨细胞数（P<0.01）且显著增加去卵巢大鼠股骨骨密度（P<0.05）。
Moreover, Er-xian decoction obviously reduced osteoclast number(P<0.01)and enhanced bone density of femur metaphysis in ovariectomized rats(P<0.05).
减少破骨细胞数（P<0.01）且显著增加去卵巢大鼠股骨骨密度（P<0.05）。
Moreover, Er-xian decoction obviously reduced osteoclast number(P<0.01)and enhanced bone density of femur metaphysis in ovariectomized rats(P<0.05).
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