结果:合成了盐酸吉西他滨,总收率15.8%。
目的:合成抗癌药物盐酸吉西他滨并改进合成工艺。
Objective: To synthesize of gemcitabine hydrochloride and optimize the process.
目的:评价国产药与进口药盐酸吉西他滨治疗非小细胞肺癌(NSCLC)的疗效、安全性及不良反应。
Objective: To evaluate the curative effect, safety and adverse reaction of domestic and imported gemcitabine hydrochloride in non-small cell lung cancer (NSCLC).
该工业化生产盐酸吉西他滨的合 成工艺总收率为17.9%,纯度在99.8%以上,特别适用于工业化生产盐酸 吉西他滨。
The total yield of the synthesis process is 17.9 percent and the purity is above 99.8 percent, thus being particularly applicable to the industrial production of gemcitabine hydrochloride.
该工业化生产盐酸吉西他滨的合 成工艺总收率为17.9%,纯度在99.8%以上,特别适用于工业化生产盐酸 吉西他滨。
The total yield of the synthesis process is 17.9 percent and the purity is above 99.8 percent, thus being particularly applicable to the industrial production of gemcitabine hydrochloride.
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